Downregulation of G2/mitotic-specific cyclinB1 triggers autophagy via AMPK-ULK1-dependent signal pathway in nasopharyngeal carcinoma cells

CyclinB1 is a regulatory protein involved in mitosis. Multiple lines of evidence indicate that cyclinB1 depletion constrains proliferation and induces apoptosis in human tumor cells. The cells become susceptible to suffer a critical situation when cyclinB1 is downregulated. Autophagy is a major intr...

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Veröffentlicht in:	Cell death & disease 2019-01, Vol.10 (2), p.94-94, Article 94
Hauptverfasser:	Xie, Xianhe, Lin, Wanzun, Zheng, Weili, Chen, Ting, Yang, Haitao, Sun, Lijun, Huang, Fei, Wang, Zili, Lin, Heng, Chen, Long, Liu, Jun, Yang, Liyan
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/31 13/51 13/89 13/95 14/19 14/28 14/63 38/47 45/90 631/67/395 631/80/39/2346 Antibodies Apoptosis Autophagy Biochemistry Biomedical and Life Sciences Cell Biology Cell Culture Cell cycle Cell proliferation Cell survival Immunology Life Sciences Mitosis Nasopharyngeal carcinoma Nutrients Organelles Phagocytosis Phosphorylation Throat cancer Tumor cells
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