Pirfenidone, an Anti-Fibrotic Drug, Suppresses the Growth of Human Prostate Cancer Cells by Inducing G₁ Cell Cycle Arrest

Pirfenidone (PFD) is an anti-fibrotic drug used to treat idiopathic pulmonary fibrosis by inducing G₁ cell cycle arrest in fibroblasts. We hypothesize that PFD can induce G₁ cell cycle arrest in different types of cells, including cancer cells. To investigate the effects of PFD treatment on the grow...

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Veröffentlicht in:	Journal of clinical medicine 2019-01, Vol.8 (1), p.44
Hauptverfasser:	Ishii, Kenichiro, Sasaki, Takeshi, Iguchi, Kazuhiro, Kato, Manabu, Kanda, Hideki, Hirokawa, Yoshifumi, Arima, Kiminobu, Watanabe, Masatoshi, Sugimura, Yoshiki
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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