Vinyl sulfonamide synthesis for irreversible tethering via a novel α-selenoether protection strategy† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8md00566d

A novel strategy for the synthesis of vinyl sulfonamide fragments for application to irreversible protein tethering. Vinyl sulfonamides are valuable electrophiles for targeted protein modification and inhibition. We describe a novel approach to the synthesis of terminal vinyl sulfonamides which uses...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	MedChemComm 2018-12, Vol.10 (1), p.158-163
Hauptverfasser:	Craven, Gregory B., Affron, Dominic P., Raymond, Philip N., Mann, David J., Armstrong, Alan
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!