Developmental Programming: Impact of Prenatal Testosterone Excess on Steroidal Machinery and Cell Differentiation Markers in Visceral Adipocytes of Female Sheep

Prenatal testosterone (T)-treated female sheep manifest reduced adipocyte size and peripheral insulin resistance. The small adipocyte phenotype may reflect defects in adipogenesis and its steroidal machinery. To test whether prenatal T treatment from gestational days 30 to 90 alters the visceral adi...

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Veröffentlicht in:	Reproductive sciences (Thousand Oaks, Calif.) Calif.), 2018-07, Vol.25 (7), p.1010-1023
Hauptverfasser:	Puttabyatappa, Muraly, Lu, Chunxia, Martin, Jacob D., Chazenbalk, Gregorio, Dumesic, Daniel, Padmanabhan, Vasantha
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - drug effects Adipocytes - metabolism Adipogenesis Androgen Receptor Antagonists - administration & dosage Androgens - administration & dosage Androgens - metabolism Animals Embryology Female Humans Intra-Abdominal Fat - drug effects Intra-Abdominal Fat - growth & development Intra-Abdominal Fat - metabolism Medicine & Public Health Mesenchymal Stem Cells - drug effects Mesenchymal Stem Cells - metabolism Obstetrics/Perinatology/Midwifery Original Original Article Pregnancy Receptors, Androgen - metabolism Reproductive Medicine Sheep, Domestic Testosterone - administration & dosage Testosterone - metabolism
Online-Zugang:	Volltext
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