Negative pressure wound therapy in the treatment of diabetic foot ulcers may be mediated through differential gene expression

Aims Negative pressure wound therapy (NPWT) has been successfully used as a treatment for diabetic foot ulceration (DFU). Its mechanism of action on the molecular level, however, is not fully understood. We assessed the effect of NPWT on gene expression in patients with type 2 diabetes (T2DM) and DF...

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Veröffentlicht in:	Acta diabetologica 2019-01, Vol.56 (1), p.115-120
Hauptverfasser:	Borys, S., Ludwig-Slomczynska, A. H., Seweryn, M., Hohendorff, J., Koblik, T., Machlowska, J., Kiec-Wilk, B., Wolkow, P., Malecki, Maciej T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Angiogenesis Carrier Proteins - genetics Case-Control Studies Complement component C1q Data processing Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - genetics Diabetes Mellitus, Type 2 - therapy Diabetic Foot - genetics Diabetic Foot - metabolism Diabetic Foot - therapy Feet Female Foot diseases Gene expression Gene Expression Profiling Gene Expression Regulation Glial cell line-derived neurotrophic factor Humans Inositol 1,4,5-trisphosphate receptors Internal Medicine Leg ulcers Male Medicine Medicine & Public Health Metabolic Diseases Middle Aged Mitochondrial Proteins - genetics Molecular modelling Negative-Pressure Wound Therapy Original Original Article Patients Pressure Pressure ulcers Protein interaction Proteins rab GTP-Binding Proteins - genetics Ribonucleic acid RNA Ulcers Wound healing Wound Healing - genetics
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