Sex-specific moderation by lifestyle and psychosocial factors on the genetic contributions to adiposity in 112,151 individuals from UK Biobank

Evidence suggests that lifestyle factors, e.g. physical activity, moderate the manifestation of genetic susceptibility to obesity. The present study uses UK Biobank data to investigate interaction between polygenic scores (PGS) for two obesity indicators, and lifestyle and psychosocial factors in th...

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Veröffentlicht in:	Scientific reports 2019-01, Vol.9 (1), p.363-363, Article 363
Hauptverfasser:	Calvin, Catherine M., Hagenaars, Saskia P., Gallacher, John, Harris, Sarah E., Davies, Gail, Liewald, David C., Gale, Catharine R., Deary, Ian J.
Format:	Artikel
Sprache:	eng
Schlagworte:	45/43 692/308/2056 692/499 692/699/1702/393 Adipose tissue Adiposity - genetics Adult Aged Alcohol Body Mass Index Disease Susceptibility Female Gene-Environment Interaction Genetic Predisposition to Disease Genetic Variation Health risk assessment Hip Humanities and Social Sciences Humans Income Life Style Lifestyles Male Mental Health Middle Aged multidisciplinary Neurosis Obesity Obesity - epidemiology Obesity - etiology Overweight - epidemiology Overweight - etiology Phylogeny Physical activity Public Health Surveillance Quality control Regression analysis Risk Assessment Risk Factors Science Science (multidisciplinary) Sex Factors United Kingdom - epidemiology
Online-Zugang:	Volltext
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