Batf3+ DCs and type I IFN are critical for the efficacy of neoadjuvant cancer immunotherapy

New clinical trials are now evaluating the efficacy of neoadjuvant immunotherapy in the context of primary tumor surgery. Using the orthotopic 4T1.2 mouse model of spontaneously metastatic mammary cancer, we have shown that neoadjuvant immunotherapy and surgery was superior in the generation of tumo...

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Veröffentlicht in:	Oncoimmunology 2019-02, Vol.8 (2), p.e1546068-e1546068
Hauptverfasser:	Liu, Jing, Rozeman, Elisa A., O'Donnell, Jake S., Allen, Stacey, Fanchi, Lorenzo, Smyth, Mark J., Blank, Christian U., Teng, Michele W.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Batf3 batf3+ dc metastases mouse models Neoadjuvant immunotherapy Original Research surgery type I IFN
Online-Zugang:	Volltext
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