Reasons for Exclusion from a Smoking Cessation Trial: An Analysis by Race/Ethnicity
The exclusion criteria of tobacco cessation randomized clinical trials (RCTs) may have unintended consequences on inclusion and cessation disparities. We examined racial/ethnic differences in: a) exclusion from a group-based cessation RCT; and b) reasons for exclusion. Quasi-experimental. Inclusion...
Gespeichert in:
| Veröffentlicht in: | Ethnicity & disease 2019, Vol.29 (1), p.23-30 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 30 |
|---|---|
| container_issue | 1 |
| container_start_page | 23 |
| container_title | Ethnicity & disease |
| container_volume | 29 |
| creator | Hooper, Monica Webb Asfar, Taghrid Unrod, Marina Dorsey, Asha Correa, John B. Brandon, Karen O. Simmons, Vani N. Antoni, Michael A. Koru-Sengul, Tulay Lee, David J. Brandon, Thomas H. |
| description | The exclusion criteria of tobacco cessation randomized clinical trials (RCTs) may have unintended consequences on inclusion and cessation disparities. We examined racial/ethnic differences in: a) exclusion from a group-based cessation RCT; and b) reasons for exclusion.
Quasi-experimental. Inclusion criteria were self-identification as African American/Black, non-Hispanic White, or Hispanic (any race), adults, minimum five cigarettes/day or carbon monoxide reading of ≥ 8 parts per million (ppm), interest in quitting, and spoke/read English. Data were obtained from a parent trial, which is ongoing and will be completed in 2019. Analyses for our present study on participant screening and enrollment were conducted in 2018.
Study ineligibility, and reasons for exclusion (contraindications for nicotine patch use, serious mental illness [SMI, eg, bipolar disorder or schizophrenia], alcohol dependence or illicit drug use, current tobacco treatment, attendance barriers [eg, transportation], and other concerns [eg, aggressive, intoxicated, disruptive, visibly ill]).
Of 1,206 individuals screened, 36% were ineligible. The most frequent reasons were SMI (28%), alcohol dependence or drug use (10%), and attendance barriers (7%). Ineligibility was greater among African Americans (42%) and Hispanics (37%), compared with Whites (24%; P |
| doi_str_mv | 10.18865/ed.29.1.23 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6343546</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>48668448</jstor_id><sourcerecordid>48668448</sourcerecordid><originalsourceid>FETCH-LOGICAL-c366t-81e7c184081972cf2bc8414f4b9fe87a8032b94667e6c2bb73d13c32482f4313</originalsourceid><addsrcrecordid>eNpVkM9LwzAUx4Mobk5PnpUeBenMS17T9CLImD9gIOgO3kKapbOzbWbSiv73bm4OPb0Hnw_f9_gScgp0CFKK5MrOhiwbwpDxPdKHDJOYSib2VzvFLE6AvvTIUQgLSlmSIB6SHqcpcATeJ_hkdXBNiArno_GnqbpQuiYqvKsjHT3X7q1s5tHIhqDbNZj6UlfH5KDQVbAn2zkg09vxdHQfTx7vHkY3k9hwIdpYgk0NSKQSspSZguVGImCBeVZYmWpJOcszFCK1wrA8T_kMuOEMJSuQAx-Q603ssstrOzO2ab2u1NKXtfZfyulS_SdN-arm7kMJjjxBsQq42AZ4997Z0Kq6DMZWlW6s64JikGYJByn4Sr3cqMa7ELwtdmeAqp-alZ0plilQbG2f__1s5_72uhLONsIitM7vOEohJKLk31bbgTg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2179531863</pqid></control><display><type>article</type><title>Reasons for Exclusion from a Smoking Cessation Trial: An Analysis by Race/Ethnicity</title><source>MEDLINE</source><source>JSTOR Archive Collection A-Z Listing</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Hooper, Monica Webb ; Asfar, Taghrid ; Unrod, Marina ; Dorsey, Asha ; Correa, John B. ; Brandon, Karen O. ; Simmons, Vani N. ; Antoni, Michael A. ; Koru-Sengul, Tulay ; Lee, David J. ; Brandon, Thomas H.</creator><creatorcontrib>Hooper, Monica Webb ; Asfar, Taghrid ; Unrod, Marina ; Dorsey, Asha ; Correa, John B. ; Brandon, Karen O. ; Simmons, Vani N. ; Antoni, Michael A. ; Koru-Sengul, Tulay ; Lee, David J. ; Brandon, Thomas H.</creatorcontrib><description>The exclusion criteria of tobacco cessation randomized clinical trials (RCTs) may have unintended consequences on inclusion and cessation disparities. We examined racial/ethnic differences in: a) exclusion from a group-based cessation RCT; and b) reasons for exclusion.
Quasi-experimental. Inclusion criteria were self-identification as African American/Black, non-Hispanic White, or Hispanic (any race), adults, minimum five cigarettes/day or carbon monoxide reading of ≥ 8 parts per million (ppm), interest in quitting, and spoke/read English. Data were obtained from a parent trial, which is ongoing and will be completed in 2019. Analyses for our present study on participant screening and enrollment were conducted in 2018.
Study ineligibility, and reasons for exclusion (contraindications for nicotine patch use, serious mental illness [SMI, eg, bipolar disorder or schizophrenia], alcohol dependence or illicit drug use, current tobacco treatment, attendance barriers [eg, transportation], and other concerns [eg, aggressive, intoxicated, disruptive, visibly ill]).
Of 1,206 individuals screened, 36% were ineligible. The most frequent reasons were SMI (28%), alcohol dependence or drug use (10%), and attendance barriers (7%). Ineligibility was greater among African Americans (42%) and Hispanics (37%), compared with Whites (24%; P<.001). Compared with African Americans and Hispanics, Whites were more likely to be excluded for single reasons, including attendance barriers, and medical conditions (P<.05). African Americans were more than twice as likely as Whites to be excluded for 3 or more reasons (12% vs 5% respectively, P<.05).
A notable proportion of smokers were ineligible for this RCT, with SMI as the greatest single cause. Racial/ethnic minorities were more likely to be excluded, with African Americans deemed ineligible for multiple reasons. Findings have implications for RCT generalizability, addressing tobacco disparities and health equity.</description><identifier>ISSN: 1049-510X</identifier><identifier>EISSN: 1945-0826</identifier><identifier>DOI: 10.18865/ed.29.1.23</identifier><identifier>PMID: 30713413</identifier><language>eng</language><publisher>United States: Ethnicity & Disease, Inc</publisher><subject>Adolescent ; Adult ; Continental Population Groups ; Ethnic Groups ; Female ; Florida - epidemiology ; Humans ; Male ; Middle Aged ; Original Report: Cancer ; Patient Selection ; Prevalence ; Smokers - statistics & numerical data ; Smoking Cessation - ethnology ; Smoking Cessation - statistics & numerical data ; Tobacco Products - statistics & numerical data ; Tobacco Use Cessation Devices - statistics & numerical data ; Young Adult</subject><ispartof>Ethnicity & disease, 2019, Vol.29 (1), p.23-30</ispartof><rights>Copyright © 2019, Ethnicity & Disease, Inc. 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c366t-81e7c184081972cf2bc8414f4b9fe87a8032b94667e6c2bb73d13c32482f4313</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/48668448$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/48668448$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,727,780,784,803,885,27915,27916,53782,53784,58008,58241</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30713413$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hooper, Monica Webb</creatorcontrib><creatorcontrib>Asfar, Taghrid</creatorcontrib><creatorcontrib>Unrod, Marina</creatorcontrib><creatorcontrib>Dorsey, Asha</creatorcontrib><creatorcontrib>Correa, John B.</creatorcontrib><creatorcontrib>Brandon, Karen O.</creatorcontrib><creatorcontrib>Simmons, Vani N.</creatorcontrib><creatorcontrib>Antoni, Michael A.</creatorcontrib><creatorcontrib>Koru-Sengul, Tulay</creatorcontrib><creatorcontrib>Lee, David J.</creatorcontrib><creatorcontrib>Brandon, Thomas H.</creatorcontrib><title>Reasons for Exclusion from a Smoking Cessation Trial: An Analysis by Race/Ethnicity</title><title>Ethnicity & disease</title><addtitle>Ethn Dis</addtitle><description>The exclusion criteria of tobacco cessation randomized clinical trials (RCTs) may have unintended consequences on inclusion and cessation disparities. We examined racial/ethnic differences in: a) exclusion from a group-based cessation RCT; and b) reasons for exclusion.
Quasi-experimental. Inclusion criteria were self-identification as African American/Black, non-Hispanic White, or Hispanic (any race), adults, minimum five cigarettes/day or carbon monoxide reading of ≥ 8 parts per million (ppm), interest in quitting, and spoke/read English. Data were obtained from a parent trial, which is ongoing and will be completed in 2019. Analyses for our present study on participant screening and enrollment were conducted in 2018.
Study ineligibility, and reasons for exclusion (contraindications for nicotine patch use, serious mental illness [SMI, eg, bipolar disorder or schizophrenia], alcohol dependence or illicit drug use, current tobacco treatment, attendance barriers [eg, transportation], and other concerns [eg, aggressive, intoxicated, disruptive, visibly ill]).
Of 1,206 individuals screened, 36% were ineligible. The most frequent reasons were SMI (28%), alcohol dependence or drug use (10%), and attendance barriers (7%). Ineligibility was greater among African Americans (42%) and Hispanics (37%), compared with Whites (24%; P<.001). Compared with African Americans and Hispanics, Whites were more likely to be excluded for single reasons, including attendance barriers, and medical conditions (P<.05). African Americans were more than twice as likely as Whites to be excluded for 3 or more reasons (12% vs 5% respectively, P<.05).
A notable proportion of smokers were ineligible for this RCT, with SMI as the greatest single cause. Racial/ethnic minorities were more likely to be excluded, with African Americans deemed ineligible for multiple reasons. Findings have implications for RCT generalizability, addressing tobacco disparities and health equity.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Continental Population Groups</subject><subject>Ethnic Groups</subject><subject>Female</subject><subject>Florida - epidemiology</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Original Report: Cancer</subject><subject>Patient Selection</subject><subject>Prevalence</subject><subject>Smokers - statistics & numerical data</subject><subject>Smoking Cessation - ethnology</subject><subject>Smoking Cessation - statistics & numerical data</subject><subject>Tobacco Products - statistics & numerical data</subject><subject>Tobacco Use Cessation Devices - statistics & numerical data</subject><subject>Young Adult</subject><issn>1049-510X</issn><issn>1945-0826</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkM9LwzAUx4Mobk5PnpUeBenMS17T9CLImD9gIOgO3kKapbOzbWbSiv73bm4OPb0Hnw_f9_gScgp0CFKK5MrOhiwbwpDxPdKHDJOYSib2VzvFLE6AvvTIUQgLSlmSIB6SHqcpcATeJ_hkdXBNiArno_GnqbpQuiYqvKsjHT3X7q1s5tHIhqDbNZj6UlfH5KDQVbAn2zkg09vxdHQfTx7vHkY3k9hwIdpYgk0NSKQSspSZguVGImCBeVZYmWpJOcszFCK1wrA8T_kMuOEMJSuQAx-Q603ssstrOzO2ab2u1NKXtfZfyulS_SdN-arm7kMJjjxBsQq42AZ4997Z0Kq6DMZWlW6s64JikGYJByn4Sr3cqMa7ELwtdmeAqp-alZ0plilQbG2f__1s5_72uhLONsIitM7vOEohJKLk31bbgTg</recordid><startdate>2019</startdate><enddate>2019</enddate><creator>Hooper, Monica Webb</creator><creator>Asfar, Taghrid</creator><creator>Unrod, Marina</creator><creator>Dorsey, Asha</creator><creator>Correa, John B.</creator><creator>Brandon, Karen O.</creator><creator>Simmons, Vani N.</creator><creator>Antoni, Michael A.</creator><creator>Koru-Sengul, Tulay</creator><creator>Lee, David J.</creator><creator>Brandon, Thomas H.</creator><general>Ethnicity & Disease, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>2019</creationdate><title>Reasons for Exclusion from a Smoking Cessation Trial</title><author>Hooper, Monica Webb ; Asfar, Taghrid ; Unrod, Marina ; Dorsey, Asha ; Correa, John B. ; Brandon, Karen O. ; Simmons, Vani N. ; Antoni, Michael A. ; Koru-Sengul, Tulay ; Lee, David J. ; Brandon, Thomas H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c366t-81e7c184081972cf2bc8414f4b9fe87a8032b94667e6c2bb73d13c32482f4313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Continental Population Groups</topic><topic>Ethnic Groups</topic><topic>Female</topic><topic>Florida - epidemiology</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Original Report: Cancer</topic><topic>Patient Selection</topic><topic>Prevalence</topic><topic>Smokers - statistics & numerical data</topic><topic>Smoking Cessation - ethnology</topic><topic>Smoking Cessation - statistics & numerical data</topic><topic>Tobacco Products - statistics & numerical data</topic><topic>Tobacco Use Cessation Devices - statistics & numerical data</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hooper, Monica Webb</creatorcontrib><creatorcontrib>Asfar, Taghrid</creatorcontrib><creatorcontrib>Unrod, Marina</creatorcontrib><creatorcontrib>Dorsey, Asha</creatorcontrib><creatorcontrib>Correa, John B.</creatorcontrib><creatorcontrib>Brandon, Karen O.</creatorcontrib><creatorcontrib>Simmons, Vani N.</creatorcontrib><creatorcontrib>Antoni, Michael A.</creatorcontrib><creatorcontrib>Koru-Sengul, Tulay</creatorcontrib><creatorcontrib>Lee, David J.</creatorcontrib><creatorcontrib>Brandon, Thomas H.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Ethnicity & disease</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hooper, Monica Webb</au><au>Asfar, Taghrid</au><au>Unrod, Marina</au><au>Dorsey, Asha</au><au>Correa, John B.</au><au>Brandon, Karen O.</au><au>Simmons, Vani N.</au><au>Antoni, Michael A.</au><au>Koru-Sengul, Tulay</au><au>Lee, David J.</au><au>Brandon, Thomas H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reasons for Exclusion from a Smoking Cessation Trial: An Analysis by Race/Ethnicity</atitle><jtitle>Ethnicity & disease</jtitle><addtitle>Ethn Dis</addtitle><date>2019</date><risdate>2019</risdate><volume>29</volume><issue>1</issue><spage>23</spage><epage>30</epage><pages>23-30</pages><issn>1049-510X</issn><eissn>1945-0826</eissn><abstract>The exclusion criteria of tobacco cessation randomized clinical trials (RCTs) may have unintended consequences on inclusion and cessation disparities. We examined racial/ethnic differences in: a) exclusion from a group-based cessation RCT; and b) reasons for exclusion.
Quasi-experimental. Inclusion criteria were self-identification as African American/Black, non-Hispanic White, or Hispanic (any race), adults, minimum five cigarettes/day or carbon monoxide reading of ≥ 8 parts per million (ppm), interest in quitting, and spoke/read English. Data were obtained from a parent trial, which is ongoing and will be completed in 2019. Analyses for our present study on participant screening and enrollment were conducted in 2018.
Study ineligibility, and reasons for exclusion (contraindications for nicotine patch use, serious mental illness [SMI, eg, bipolar disorder or schizophrenia], alcohol dependence or illicit drug use, current tobacco treatment, attendance barriers [eg, transportation], and other concerns [eg, aggressive, intoxicated, disruptive, visibly ill]).
Of 1,206 individuals screened, 36% were ineligible. The most frequent reasons were SMI (28%), alcohol dependence or drug use (10%), and attendance barriers (7%). Ineligibility was greater among African Americans (42%) and Hispanics (37%), compared with Whites (24%; P<.001). Compared with African Americans and Hispanics, Whites were more likely to be excluded for single reasons, including attendance barriers, and medical conditions (P<.05). African Americans were more than twice as likely as Whites to be excluded for 3 or more reasons (12% vs 5% respectively, P<.05).
A notable proportion of smokers were ineligible for this RCT, with SMI as the greatest single cause. Racial/ethnic minorities were more likely to be excluded, with African Americans deemed ineligible for multiple reasons. Findings have implications for RCT generalizability, addressing tobacco disparities and health equity.</abstract><cop>United States</cop><pub>Ethnicity & Disease, Inc</pub><pmid>30713413</pmid><doi>10.18865/ed.29.1.23</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1049-510X |
| ispartof | Ethnicity & disease, 2019, Vol.29 (1), p.23-30 |
| issn | 1049-510X 1945-0826 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6343546 |
| source | MEDLINE; JSTOR Archive Collection A-Z Listing; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Adolescent Adult Continental Population Groups Ethnic Groups Female Florida - epidemiology Humans Male Middle Aged Original Report: Cancer Patient Selection Prevalence Smokers - statistics & numerical data Smoking Cessation - ethnology Smoking Cessation - statistics & numerical data Tobacco Products - statistics & numerical data Tobacco Use Cessation Devices - statistics & numerical data Young Adult |
| title | Reasons for Exclusion from a Smoking Cessation Trial: An Analysis by Race/Ethnicity |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-14T23%3A30%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Reasons%20for%20Exclusion%20from%20a%20Smoking%20Cessation%20Trial:%20An%20Analysis%20by%20Race/Ethnicity&rft.jtitle=Ethnicity%20&%20disease&rft.au=Hooper,%20Monica%20Webb&rft.date=2019&rft.volume=29&rft.issue=1&rft.spage=23&rft.epage=30&rft.pages=23-30&rft.issn=1049-510X&rft.eissn=1945-0826&rft_id=info:doi/10.18865/ed.29.1.23&rft_dat=%3Cjstor_pubme%3E48668448%3C/jstor_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2179531863&rft_id=info:pmid/30713413&rft_jstor_id=48668448&rfr_iscdi=true |