Characterization of neurite dystrophy after trauma by high speed structured illumination microscopy and lattice light sheet microscopy

•A novel means of transecting neurites mounted on a lattice light sheet microscope is presented.•A novel means of quantifying neurite dystrophy in a structured illumination microscopy image is presented.•The neurites of human induced pluripotent stem cell-derived neurons have immature actin cytoskel...

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Veröffentlicht in:	Journal of neuroscience methods 2019-01, Vol.312, p.154-161
Hauptverfasser:	Phillips, Jack K., Sherman, Sydney A., Cotton, Kristen Y., Heddleston, John M., Taylor, Aaron B., Finan, John D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Cytoskeleton - pathology Brain Injuries - diagnostic imaging Brain Injuries - pathology Dystrophy Human induced pluripotent stem cell derived neurons Humans Induced Pluripotent Stem Cells Lattice light sheet microscopy Microscopy, Fluorescence - instrumentation Microscopy, Fluorescence - methods Neurites - pathology Neurons - pathology Structured illumination microscopy Traumatic brain injury
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