MMP-1 is overexpressed in triple-negative breast cancer tissues and the knockdown of MMP-1 expression inhibits tumor cell malignant behaviors in vitro

Matrix metalloproteinase 1 (MMP-1) is a member of the zinc-dependent endopeptidase family, which cleaves the extracellular matrix. The present study investigated the functional role of MMP-1 in breast cancer and in order to determine the underlying molecular mechanisms. The levels of MMP-1 were anal...

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Veröffentlicht in:	Oncology letters 2019-02, Vol.17 (2), p.1732-1740
Hauptverfasser:	Wang, Qi-Min, Lv, Li, Tang, Ying, Zhang, Li, Wang, Li-Fen
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Breast cancer Cancer cells Cancer metastasis Cancer prevention Cancer research Cancer therapies Cancer treatment Care and treatment Cell adhesion & migration Development and progression Epidermal growth factor Epidermal growth factors Estrogens Extracellular matrix Future predictions Gene expression Genetic aspects Health aspects Hospitals Immunohistochemistry Kinases Lymphomas Medical prognosis Medical research Metastasis Phenols (Class of compounds) Proteases Protein kinases Proteins RNA Tumors
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