The effect of regadenoson on the integrity of the human blood–brain barrier, a pilot study

Regadenoson is an FDA approved adenosine receptor agonist which increases blood–brain barrier (BBB) permeability in rodents. Regadenoson is used clinically for pharmacologic cardiac stress testing using SPECT or CT imaging agents that do not cross an intact BBB. This study was conducted to determine...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neuro-oncology 2017-05, Vol.132 (3), p.513-519
Hauptverfasser:	Jackson, Sadhana, George, Richard T., Lodge, Martin A., Piotrowski, Anna, Wahl, Richard L., Gujar, Sachin K., Grossman, Stuart A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Adenosine A2 Receptor Agonists - pharmacokinetics Aged Blood-brain barrier Blood-Brain Barrier - drug effects Brain - diagnostic imaging Brain cancer Brain tumors Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography Central nervous system Clinical Study Computed tomography Contrast Media Dextran Female Heart diseases Humans Male Medicine Medicine & Public Health Membrane permeability Middle Aged Neuroimaging Neuroimaging - methods Neurology Oncology Permeability Pilot Projects Purines - pharmacokinetics Pyrazoles - pharmacokinetics Radiopharmaceuticals Single photon emission computed tomography Studies Technetium Tc 99m Medronate Temozolomide Tomography, X-Ray Computed
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!