Oxyresveratrol Increases Energy Expenditure through Foxo3a-Mediated Ucp1 Induction in High-Fat-Diet-Induced Obese Mice

The phytochemical oxyresveratrol has been shown to exert diverse biological activities including prevention of obesity. However, the exact reason underlying the anti-obese effects of oxyresveratrol is not fully understood. Here, we investigated the effects and mechanism of oxyresveratrol in adipocyt...

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Veröffentlicht in:	International journal of molecular sciences 2018-12, Vol.20 (1), p.26
Hauptverfasser:	Choi, Jin Hee, Song, No-Joon, Lee, A Reum, Lee, Dong Ho, Seo, Min-Ju, Kim, Suji, Chang, Seo-Hyuk, Yang, Dong Kwon, Hwang, Yu-Jin, Hwang, Kyung-A, Ha, Tal Soo, Yun, Ui Jeong, Park, Kye Won
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3-L1 Cells Adenosine Adenosine kinase Adenosine monophosphate Adipocytes Adipocytes - drug effects Adipocytes - metabolism Adipose Tissue - drug effects Adipose Tissue - metabolism Animals Capsaicin receptors Cell Differentiation - drug effects Cell Line Cell Survival - drug effects Diet, High-Fat - adverse effects Energy Energy expenditure Energy intake Energy Metabolism - drug effects Forkhead Box Protein O3 - metabolism FOXO3 protein Gene expression Gene Expression Regulation High fat diet Kinases Lipid Metabolism - drug effects Lipids Male Metabolic disorders Metabolic rate Metabolomics - methods Mice Mitochondria Obesity Obesity - etiology Obesity - metabolism Phytochemicals Plant Extracts - pharmacology Protein kinase Proteins Stilbenes - pharmacology Stimulators Thermogenesis - genetics Toxicity Transcription Triglycerides Uncoupling Protein 1 - genetics Uncoupling Protein 1 - metabolism Weight control
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