Case Report: Central Nervous System Strongyloidiasis: Two Cases Diagnosed Antemortem

Central nervous system (CNS) strongyloidiasis is a known but rare form of disseminated infection. The diagnosis is often made postmortem, with only five published cases of an antemortem diagnosis. We report two fatal cases of CNS strongyloidiasis diagnosed antemortem, with larvae visualized in the C...

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Veröffentlicht in:The American journal of tropical medicine and hygiene 2019-01, Vol.100 (1), p.130-134
Hauptverfasser: Tam, Jennifer, Schwartz, Kevin L, Keystone, Jay, Dimitrakoudis, Dimitri, Downing, Mark, Krajden, Sigmund
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container_title The American journal of tropical medicine and hygiene
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creator Tam, Jennifer
Schwartz, Kevin L
Keystone, Jay
Dimitrakoudis, Dimitri
Downing, Mark
Krajden, Sigmund
description Central nervous system (CNS) strongyloidiasis is a known but rare form of disseminated infection. The diagnosis is often made postmortem, with only five published cases of an antemortem diagnosis. We report two fatal cases of CNS strongyloidiasis diagnosed antemortem, with larvae visualized in the CNS sample in one case. Risk factors for disseminated strongyloidiasis common to both cases included origination from the Caribbean, underlying human T-lymphotropic virus-1 infection, and recent prednisone use. Both cases occurred in Canada, where the occurrence of is uncommon, and serve as a reminder to maintain a high index of suspicion in patients with epidemiologic or clinical risk factors for dissemination.
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subjects Aged
Animals
Canada
Caribbean Region
Case reports
Central Nervous System - parasitology
Diagnosis
Fatal Outcome
Female
HTLV-I Infections - complications
Humans
Male
Middle Aged
Nervous system
Parasitic diseases
Prednisone - adverse effects
Risk Factors
Strongyloides stercoralis - isolation & purification
Strongyloidiasis - blood
Strongyloidiasis - diagnosis
title Case Report: Central Nervous System Strongyloidiasis: Two Cases Diagnosed Antemortem
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