Case Report: Central Nervous System Strongyloidiasis: Two Cases Diagnosed Antemortem
Central nervous system (CNS) strongyloidiasis is a known but rare form of disseminated infection. The diagnosis is often made postmortem, with only five published cases of an antemortem diagnosis. We report two fatal cases of CNS strongyloidiasis diagnosed antemortem, with larvae visualized in the C...
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Veröffentlicht in: | The American journal of tropical medicine and hygiene 2019-01, Vol.100 (1), p.130-134 |
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description | Central nervous system (CNS) strongyloidiasis is a known but rare form of disseminated infection. The diagnosis is often made postmortem, with only five published cases of an antemortem diagnosis. We report two fatal cases of CNS strongyloidiasis diagnosed antemortem, with
larvae visualized in the CNS sample in one case. Risk factors for disseminated strongyloidiasis common to both cases included origination from the Caribbean, underlying human T-lymphotropic virus-1 infection, and recent prednisone use. Both cases occurred in Canada, where the occurrence of
is uncommon, and serve as a reminder to maintain a high index of suspicion in patients with epidemiologic or clinical risk factors for dissemination. |
doi_str_mv | 10.4269/ajtmh.18-0813 |
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larvae visualized in the CNS sample in one case. Risk factors for disseminated strongyloidiasis common to both cases included origination from the Caribbean, underlying human T-lymphotropic virus-1 infection, and recent prednisone use. Both cases occurred in Canada, where the occurrence of
is uncommon, and serve as a reminder to maintain a high index of suspicion in patients with epidemiologic or clinical risk factors for dissemination.</description><subject>Aged</subject><subject>Animals</subject><subject>Canada</subject><subject>Caribbean Region</subject><subject>Case reports</subject><subject>Central Nervous System - parasitology</subject><subject>Diagnosis</subject><subject>Fatal Outcome</subject><subject>Female</subject><subject>HTLV-I Infections - complications</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Nervous system</subject><subject>Parasitic diseases</subject><subject>Prednisone - adverse effects</subject><subject>Risk Factors</subject><subject>Strongyloides stercoralis - isolation & purification</subject><subject>Strongyloidiasis - blood</subject><subject>Strongyloidiasis - diagnosis</subject><issn>0002-9637</issn><issn>1476-1645</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkc1vEzEQxS1ERUPhyBVZ4tLLFo-_twekKkCLVIFEw9lyvLPpRrvrYG-K8t_jNKUqPc3h_eZp3jxC3gE7k1zXH_16Gm7PwFbMgnhBZiCNrkBL9ZLMGGO8qrUwx-R1zmvGwHKAV-RYMKkMq9WMLOY-I_2Jm5imczrHcUq-p98x3cVtpje7POFAb6YUx9Wuj13T-dzlc7r4E-l-M9PPnV-NMWNDL8bCFhsc3pCj1vcZ3z7ME_Lr65fF_Kq6_nH5bX5xXQUJaqpaXNpQ2xYkghSKC6VQ1i2GJdSCKwOaWcZ5I0wNjaqN1S33pugtC8EEKU7Ip4PvZrscsAmH690mdYNPOxd95_5Xxu7WreKd00Ioa00xOH0wSPH3FvPkhi4H7Hs_YsnvOAjN9P5bBf3wDF3HbRpLvEIZxY2SyhaqOlAhxZwTto_HAHP7vtx9Xw6s2_dV-PdPEzzS_woSfwHqUpI6</recordid><startdate>20190101</startdate><enddate>20190101</enddate><creator>Tam, Jennifer</creator><creator>Schwartz, Kevin L</creator><creator>Keystone, Jay</creator><creator>Dimitrakoudis, Dimitri</creator><creator>Downing, Mark</creator><creator>Krajden, Sigmund</creator><general>Institute of Tropical Medicine</general><general>The American Society of Tropical Medicine and Hygiene</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20190101</creationdate><title>Case Report: Central Nervous System Strongyloidiasis: Two Cases Diagnosed Antemortem</title><author>Tam, Jennifer ; Schwartz, Kevin L ; Keystone, Jay ; Dimitrakoudis, Dimitri ; Downing, Mark ; Krajden, Sigmund</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c415t-feb8c98f14e14352355e49fecb1932571608022d3791d59786f2a7fecf0cc7c43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Aged</topic><topic>Animals</topic><topic>Canada</topic><topic>Caribbean Region</topic><topic>Case reports</topic><topic>Central Nervous System - parasitology</topic><topic>Diagnosis</topic><topic>Fatal Outcome</topic><topic>Female</topic><topic>HTLV-I Infections - complications</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Nervous system</topic><topic>Parasitic diseases</topic><topic>Prednisone - adverse effects</topic><topic>Risk Factors</topic><topic>Strongyloides stercoralis - isolation & purification</topic><topic>Strongyloidiasis - blood</topic><topic>Strongyloidiasis - diagnosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tam, Jennifer</creatorcontrib><creatorcontrib>Schwartz, Kevin L</creatorcontrib><creatorcontrib>Keystone, Jay</creatorcontrib><creatorcontrib>Dimitrakoudis, Dimitri</creatorcontrib><creatorcontrib>Downing, Mark</creatorcontrib><creatorcontrib>Krajden, Sigmund</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The American journal of tropical medicine and hygiene</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tam, Jennifer</au><au>Schwartz, Kevin L</au><au>Keystone, Jay</au><au>Dimitrakoudis, Dimitri</au><au>Downing, Mark</au><au>Krajden, Sigmund</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Case Report: Central Nervous System Strongyloidiasis: Two Cases Diagnosed Antemortem</atitle><jtitle>The American journal of tropical medicine and hygiene</jtitle><addtitle>Am J Trop Med Hyg</addtitle><date>2019-01-01</date><risdate>2019</risdate><volume>100</volume><issue>1</issue><spage>130</spage><epage>134</epage><pages>130-134</pages><issn>0002-9637</issn><eissn>1476-1645</eissn><abstract>Central nervous system (CNS) strongyloidiasis is a known but rare form of disseminated infection. 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larvae visualized in the CNS sample in one case. Risk factors for disseminated strongyloidiasis common to both cases included origination from the Caribbean, underlying human T-lymphotropic virus-1 infection, and recent prednisone use. Both cases occurred in Canada, where the occurrence of
is uncommon, and serve as a reminder to maintain a high index of suspicion in patients with epidemiologic or clinical risk factors for dissemination.</abstract><cop>United States</cop><pub>Institute of Tropical Medicine</pub><pmid>30457095</pmid><doi>10.4269/ajtmh.18-0813</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aged Animals Canada Caribbean Region Case reports Central Nervous System - parasitology Diagnosis Fatal Outcome Female HTLV-I Infections - complications Humans Male Middle Aged Nervous system Parasitic diseases Prednisone - adverse effects Risk Factors Strongyloides stercoralis - isolation & purification Strongyloidiasis - blood Strongyloidiasis - diagnosis |
title | Case Report: Central Nervous System Strongyloidiasis: Two Cases Diagnosed Antemortem |
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