α2A-Adrenergic Receptor Activation Decreases Parabrachial Nucleus Excitatory Drive onto BNST CRF Neurons and Reduces Their Activity In Vivo

Stress contributes to numerous psychiatric disorders. Corticotropin releasing factor (CRF) signaling and CRF neurons in the bed nucleus of the stria terminalis (BNST) drive negative affective behaviors, thus agents that decrease activity of these cells may be of therapeutic interest. Here, we show t...

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Veröffentlicht in:The Journal of neuroscience 2019-01, Vol.39 (3), p.472-484
Hauptverfasser: Fetterly, Tracy L, Basu, Aakash, Nabit, Brett P, Awad, Elias, Williford, Kellie M, Centanni, Samuel W, Matthews, Robert T, Silberman, Yuval, Winder, Danny G
Format: Artikel
Sprache:eng
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