Redox Regulation of Homeostasis and Proteostasis in Peroxisomes

Peroxisomes are highly dynamic intracellular organelles involved in a variety of metabolic functions essential for the metabolism of long-chain fatty acids, d-amino acids, and many polyamines. A byproduct of peroxisomal metabolism is the generation, and subsequent detoxification, of reactive oxygen...

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Veröffentlicht in:	Physiological reviews 2018-01, Vol.98 (1), p.89-115
Hauptverfasser:	Walker, Cheryl L, Pomatto, Laura C D, Tripathi, Durga Nand, Davies, Kelvin J A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Amino acids Animals Ataxia telangiectasia mutated protein Autophagy D-Amino acids Detoxification Fatty acids Heredity Homeostasis Homeostasis - drug effects Homeostasis - physiology Humans Hydrogen peroxide Hydrogen Peroxide - pharmacology Intracellular Mitochondria Mitochondria - metabolism Peroxisomes Peroxisomes - drug effects Peroxisomes - metabolism Pexophagy Phagocytosis Polyamines Proteins Proteostasis - drug effects Proteostasis - physiology Reactive nitrogen species Reactive oxygen species Reactive Oxygen Species - metabolism Review Tuberous sclerosis
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