Hacking the Matrix

Recently in Nature, Gjorevski et al. (2016) describe a fully defined synthetic hydrogel that mimics the extracellular matrix to support in vitro growth of intestinal stem cells and organoids. The hydrogel allows exquisite control over the chemical and physical in vitro niche and enables identificati...

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Veröffentlicht in:Cell stem cell 2017-01, Vol.20 (1), p.9-10
Hauptverfasser: Czerwinski, Michael, Spence, Jason R.
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description Recently in Nature, Gjorevski et al. (2016) describe a fully defined synthetic hydrogel that mimics the extracellular matrix to support in vitro growth of intestinal stem cells and organoids. The hydrogel allows exquisite control over the chemical and physical in vitro niche and enables identification of regulatory properties of the matrix. Recently in Nature, Gjorevski et al. (2016) describe a fully defined synthetic hydrogel that mimics the extracellular matrix to support in vitro growth of intestinal stem cells and organoids. The hydrogel allows exquisite control over the chemical and physical in vitro niche and enables identification of regulatory properties of the matrix.
doi_str_mv 10.1016/j.stem.2016.12.010
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subjects Extracellular Matrix - chemistry
Hydrogel, Polyethylene Glycol Dimethacrylate - analysis
Intestines
Organoids
Stem Cells
title Hacking the Matrix
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