Effect of Alkaloid Extract from African Jointfir (Gnetum africanum) Leaves on Manganese-Induced Toxicity in Drosophila melanogaster

Metal-induced toxicity in fruit fly (Drosophila melanogaster) is one of the established models for studying neurotoxicity and neurodegenerative diseases. Phytochemicals, especially alkaloids, have been reported to exhibit neuroprotection. Here, we assessed the protective effect of alkaloid extract f...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2018-01, Vol.2018 (2018), p.1-10
Hauptverfasser:	Atoki, Victor Ayomide, Awonyemi, Olatunde Isaac, Ogunsuyi, Opeyemi Babatunde, Oboh, Ganiyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - pharmacology Biochemistry Brain research Disease Drosophila melanogaster - drug effects Drosophila melanogaster - growth & development Drosophila melanogaster - metabolism Enzymes Gnetum - chemistry Insects Laboratories Leaves Manganese - toxicity Neurodegeneration Neuroprotective Agents - pharmacology Neurosciences Neurotoxicity Nitric oxide Oxidative stress Oxidative Stress - drug effects Phytochemicals Plant Extracts - pharmacology Plant Leaves - chemistry Potassium Reactive Oxygen Species - metabolism
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