Translating Alzheimer's disease–associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs

The International Genomics of Alzheimer's Project (IGAP) is a consortium for characterizing the genetic landscape of Alzheimer's disease (AD). The identified and/or confirmed 19 single-nucleotide polymorphisms (SNPs) associated with AD are located on non-coding DNA regions, and their funct...

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Veröffentlicht in:	Neurobiology of aging 2019-02, Vol.74, p.135-146
Hauptverfasser:	Katsumata, Yuriko, Nelson, Peter T., Estus, Steven, Fardo, David W.
Format:	Artikel
Sprache:	eng
Schlagworte:	ADGC ADSP Aged Aged, 80 and over Alzheimer Disease - genetics Carrier Proteins - genetics CELF1 Protein - genetics Desmoglein 2 - genetics Female Genetic Association Studies GWAS Humans Linkage Disequilibrium - genetics Male Membrane Proteins - genetics Neuroinflammation Polymorphism, Single Nucleotide - genetics Quantitative Trait Loci - genetics Receptors, N-Methyl-D-Aspartate RNA, Messenger - genetics RNA, Untranslated - genetics SAP90-PSD95 Associated Proteins - genetics Transcription, Genetic - genetics WES
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