Updates in adjuvant systemic therapy for melanoma
There has been a rapid increase in adjuvant therapies approved for treatment following surgical resection of stages III/IV melanoma. We review current indications for adjuvant therapy, which currently includes a heterogenous group of stages III and IV patients with melanoma. We describe several pivo...
Gespeichert in:
| Veröffentlicht in: | Journal of surgical oncology 2019-02, Vol.119 (2), p.222-231 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 231 |
|---|---|
| container_issue | 2 |
| container_start_page | 222 |
| container_title | Journal of surgical oncology |
| container_volume | 119 |
| creator | Kwak, Minyoung Farrow, Norma E. Salama, April K. S. Mosca, Paul J. Hanks, Brent A. Slingluff, Craig L. Beasley, Georgia M. |
| description | There has been a rapid increase in adjuvant therapies approved for treatment following surgical resection of stages III/IV melanoma. We review current indications for adjuvant therapy, which currently includes a heterogenous group of stages III and IV patients with melanoma. We describe several pivotal clinical trials of systemic immune therapies, targeted immune therapies, and adjuvant vaccine strategies. Finally, we discuss the evidence for selecting the most appropriate treatment regimen(s) for the individual patient. |
| doi_str_mv | 10.1002/jso.25298 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6330126</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2166360913</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4438-547a6451750edfe8ade111a47e4f6dadd3dbe522541c02e6e0d3210e22ac4bbc3</originalsourceid><addsrcrecordid>eNp1kU1Lw0AQhhdRtFYP_gEJeNFD2tmPbJKLIMVPhB7U87LNTjQlydbdpNJ_72q1qOBpDvPw8M68hBxRGFEANp57O2IJy7MtMqCQyziHPNsmg7BjsUhz2CP73s8BIM-l2CV7HERGeZoMCH1aGN2hj6o20mbeL3XbRX7lO2yqIupe0OnFKiqtixqsdWsbfUB2Sl17PPyaQ_J0dfk4uYnvp9e3k4v7uBCCZ3EiUi1FQtME0JSYaYOUUi1SFKU02hhuZpgwlghaAEOJYDijgIzpQsxmBR-S87V30c8aNAW2ndO1Wriq0W6lrK7U701bvahnu1SSc6BMBsHpl8DZ1x59p5rKF1iHM9D2XjHKMylYRrOAnvxB57Z3bTgvUFJyCTnlgTpbU4Wz3jssN2EoqI8iVChCfRYR2OOf6Tfk9-cDMF4Db1WNq_9N6u5hula-A_Dskm4</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2166360913</pqid></control><display><type>article</type><title>Updates in adjuvant systemic therapy for melanoma</title><source>MEDLINE</source><source>Wiley Online Library All Journals</source><creator>Kwak, Minyoung ; Farrow, Norma E. ; Salama, April K. S. ; Mosca, Paul J. ; Hanks, Brent A. ; Slingluff, Craig L. ; Beasley, Georgia M.</creator><creatorcontrib>Kwak, Minyoung ; Farrow, Norma E. ; Salama, April K. S. ; Mosca, Paul J. ; Hanks, Brent A. ; Slingluff, Craig L. ; Beasley, Georgia M.</creatorcontrib><description>There has been a rapid increase in adjuvant therapies approved for treatment following surgical resection of stages III/IV melanoma. We review current indications for adjuvant therapy, which currently includes a heterogenous group of stages III and IV patients with melanoma. We describe several pivotal clinical trials of systemic immune therapies, targeted immune therapies, and adjuvant vaccine strategies. Finally, we discuss the evidence for selecting the most appropriate treatment regimen(s) for the individual patient.</description><identifier>ISSN: 0022-4790</identifier><identifier>EISSN: 1096-9098</identifier><identifier>DOI: 10.1002/jso.25298</identifier><identifier>PMID: 30481375</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>adjuvant therapy ; Antineoplastic Combined Chemotherapy Protocols - therapeutic use ; Cancer surgery ; Cancer therapies ; Chemotherapy, Adjuvant ; Clinical trials ; Disease Management ; Humans ; Immunotherapy ; Melanoma ; Melanoma - drug therapy ; Melanoma - immunology ; Melanoma - pathology ; Prognosis ; Skin Neoplasms - drug therapy ; Skin Neoplasms - immunology ; Skin Neoplasms - pathology</subject><ispartof>Journal of surgical oncology, 2019-02, Vol.119 (2), p.222-231</ispartof><rights>2018 Wiley Periodicals, Inc.</rights><rights>2019 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4438-547a6451750edfe8ade111a47e4f6dadd3dbe522541c02e6e0d3210e22ac4bbc3</citedby><cites>FETCH-LOGICAL-c4438-547a6451750edfe8ade111a47e4f6dadd3dbe522541c02e6e0d3210e22ac4bbc3</cites><orcidid>0000-0001-6387-9030</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjso.25298$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjso.25298$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,780,784,885,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30481375$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kwak, Minyoung</creatorcontrib><creatorcontrib>Farrow, Norma E.</creatorcontrib><creatorcontrib>Salama, April K. S.</creatorcontrib><creatorcontrib>Mosca, Paul J.</creatorcontrib><creatorcontrib>Hanks, Brent A.</creatorcontrib><creatorcontrib>Slingluff, Craig L.</creatorcontrib><creatorcontrib>Beasley, Georgia M.</creatorcontrib><title>Updates in adjuvant systemic therapy for melanoma</title><title>Journal of surgical oncology</title><addtitle>J Surg Oncol</addtitle><description>There has been a rapid increase in adjuvant therapies approved for treatment following surgical resection of stages III/IV melanoma. We review current indications for adjuvant therapy, which currently includes a heterogenous group of stages III and IV patients with melanoma. We describe several pivotal clinical trials of systemic immune therapies, targeted immune therapies, and adjuvant vaccine strategies. Finally, we discuss the evidence for selecting the most appropriate treatment regimen(s) for the individual patient.</description><subject>adjuvant therapy</subject><subject>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</subject><subject>Cancer surgery</subject><subject>Cancer therapies</subject><subject>Chemotherapy, Adjuvant</subject><subject>Clinical trials</subject><subject>Disease Management</subject><subject>Humans</subject><subject>Immunotherapy</subject><subject>Melanoma</subject><subject>Melanoma - drug therapy</subject><subject>Melanoma - immunology</subject><subject>Melanoma - pathology</subject><subject>Prognosis</subject><subject>Skin Neoplasms - drug therapy</subject><subject>Skin Neoplasms - immunology</subject><subject>Skin Neoplasms - pathology</subject><issn>0022-4790</issn><issn>1096-9098</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kU1Lw0AQhhdRtFYP_gEJeNFD2tmPbJKLIMVPhB7U87LNTjQlydbdpNJ_72q1qOBpDvPw8M68hBxRGFEANp57O2IJy7MtMqCQyziHPNsmg7BjsUhz2CP73s8BIM-l2CV7HERGeZoMCH1aGN2hj6o20mbeL3XbRX7lO2yqIupe0OnFKiqtixqsdWsbfUB2Sl17PPyaQ_J0dfk4uYnvp9e3k4v7uBCCZ3EiUi1FQtME0JSYaYOUUi1SFKU02hhuZpgwlghaAEOJYDijgIzpQsxmBR-S87V30c8aNAW2ndO1Wriq0W6lrK7U701bvahnu1SSc6BMBsHpl8DZ1x59p5rKF1iHM9D2XjHKMylYRrOAnvxB57Z3bTgvUFJyCTnlgTpbU4Wz3jssN2EoqI8iVChCfRYR2OOf6Tfk9-cDMF4Db1WNq_9N6u5hula-A_Dskm4</recordid><startdate>20190201</startdate><enddate>20190201</enddate><creator>Kwak, Minyoung</creator><creator>Farrow, Norma E.</creator><creator>Salama, April K. S.</creator><creator>Mosca, Paul J.</creator><creator>Hanks, Brent A.</creator><creator>Slingluff, Craig L.</creator><creator>Beasley, Georgia M.</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-6387-9030</orcidid></search><sort><creationdate>20190201</creationdate><title>Updates in adjuvant systemic therapy for melanoma</title><author>Kwak, Minyoung ; Farrow, Norma E. ; Salama, April K. S. ; Mosca, Paul J. ; Hanks, Brent A. ; Slingluff, Craig L. ; Beasley, Georgia M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4438-547a6451750edfe8ade111a47e4f6dadd3dbe522541c02e6e0d3210e22ac4bbc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>adjuvant therapy</topic><topic>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</topic><topic>Cancer surgery</topic><topic>Cancer therapies</topic><topic>Chemotherapy, Adjuvant</topic><topic>Clinical trials</topic><topic>Disease Management</topic><topic>Humans</topic><topic>Immunotherapy</topic><topic>Melanoma</topic><topic>Melanoma - drug therapy</topic><topic>Melanoma - immunology</topic><topic>Melanoma - pathology</topic><topic>Prognosis</topic><topic>Skin Neoplasms - drug therapy</topic><topic>Skin Neoplasms - immunology</topic><topic>Skin Neoplasms - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kwak, Minyoung</creatorcontrib><creatorcontrib>Farrow, Norma E.</creatorcontrib><creatorcontrib>Salama, April K. S.</creatorcontrib><creatorcontrib>Mosca, Paul J.</creatorcontrib><creatorcontrib>Hanks, Brent A.</creatorcontrib><creatorcontrib>Slingluff, Craig L.</creatorcontrib><creatorcontrib>Beasley, Georgia M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kwak, Minyoung</au><au>Farrow, Norma E.</au><au>Salama, April K. S.</au><au>Mosca, Paul J.</au><au>Hanks, Brent A.</au><au>Slingluff, Craig L.</au><au>Beasley, Georgia M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Updates in adjuvant systemic therapy for melanoma</atitle><jtitle>Journal of surgical oncology</jtitle><addtitle>J Surg Oncol</addtitle><date>2019-02-01</date><risdate>2019</risdate><volume>119</volume><issue>2</issue><spage>222</spage><epage>231</epage><pages>222-231</pages><issn>0022-4790</issn><eissn>1096-9098</eissn><abstract>There has been a rapid increase in adjuvant therapies approved for treatment following surgical resection of stages III/IV melanoma. We review current indications for adjuvant therapy, which currently includes a heterogenous group of stages III and IV patients with melanoma. We describe several pivotal clinical trials of systemic immune therapies, targeted immune therapies, and adjuvant vaccine strategies. Finally, we discuss the evidence for selecting the most appropriate treatment regimen(s) for the individual patient.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>30481375</pmid><doi>10.1002/jso.25298</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0001-6387-9030</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-4790 |
| ispartof | Journal of surgical oncology, 2019-02, Vol.119 (2), p.222-231 |
| issn | 0022-4790 1096-9098 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6330126 |
| source | MEDLINE; Wiley Online Library All Journals |
| subjects | adjuvant therapy Antineoplastic Combined Chemotherapy Protocols - therapeutic use Cancer surgery Cancer therapies Chemotherapy, Adjuvant Clinical trials Disease Management Humans Immunotherapy Melanoma Melanoma - drug therapy Melanoma - immunology Melanoma - pathology Prognosis Skin Neoplasms - drug therapy Skin Neoplasms - immunology Skin Neoplasms - pathology |
| title | Updates in adjuvant systemic therapy for melanoma |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T05%3A55%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Updates%20in%20adjuvant%20systemic%20therapy%20for%20melanoma&rft.jtitle=Journal%20of%20surgical%20oncology&rft.au=Kwak,%20Minyoung&rft.date=2019-02-01&rft.volume=119&rft.issue=2&rft.spage=222&rft.epage=231&rft.pages=222-231&rft.issn=0022-4790&rft.eissn=1096-9098&rft_id=info:doi/10.1002/jso.25298&rft_dat=%3Cproquest_pubme%3E2166360913%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2166360913&rft_id=info:pmid/30481375&rfr_iscdi=true |