Vascular Tissue Engineering Using Scaffold-Free Prevascular Endothelial-Fibroblast Constructs

Vascularization remains a substantial limitation to the viability of engineered tissue. By comparing vascularization dynamics of a self-assembled prevascular endothelial-fibroblast model to avascular grafts, we explore the vascularization rate limitations in implants at early time intervals, during...

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Veröffentlicht in:	BioResearch open access 2019, Vol.8 (1), p.1-15
Hauptverfasser:	Pattanaik, Sanket, Arbra, Chase, Bainbridge, Heather, Dennis, Sarah Grace, Fann, Stephen A, Yost, Michael J
Format:	Artikel
Sprache:	eng
Schlagworte:	Anastomosis Angiogenesis Cell viability Extracellular matrix Fibroblasts Hypoxia Latency Microvasculature Original Pipelines Self-assembly Silicones Spheroids Stem cells Surgery Tissue engineering Transplants & implants Vascularization
Online-Zugang:	Volltext
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