Mechanotransduction of vocal fold fibroblasts and mesenchymal stromal cells in the context of the vocal fold mechanome

The design of cell-based therapies for vocal fold tissue engineering requires an understanding of how cells adapt to the dynamic mechanical forces found in the larynx. Our objective was to compare mechanotransductive processes in therapeutic cell candidates (mesenchymal stromal cells from adipose ti...

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Veröffentlicht in:	Journal of biomechanics 2019-01, Vol.83, p.227-234
Hauptverfasser:	Bartlett, Rebecca S., Gaston, Joel D., Ye, Shuyun, Kendziorski, Christina, Thibeault, Susan L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation Adipose tissue Axial stress Bayes Theorem Bayesian analysis Bioreactors Bone marrow Cell adhesion & migration Design Design engineering DNA microarrays Empirical analysis Encyclopedias Extracellular matrix Extracellular Matrix - metabolism Fibroblasts Fibroblasts - cytology Gene expression Genomes Humans Integrins Lamellipodia Larynx Mechanical properties Mechanotransduction Mechanotransduction, Cellular Mesenchymal stem cells Mesenchymal Stem Cells - cytology Mesenchymal stromal cells Mesenchyme Polystyrene Polystyrene resins Pseudopodia Stress, Mechanical Stromal cells Tensile strain Tensile stress Tissue Engineering Vibration Vocal Cords - cytology Vocal folds
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