Effects of dynamic loading on solute transport through the human cartilage endplate

Nutrient and metabolite transport through the cartilage endplate (CEP) is important for maintaining proper disc nutrition, but the mechanisms of solute transport remain unclear. One unresolved issue is the role of dynamic loading. In comparison to static loading, dynamic loading is thought to enhanc...

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Veröffentlicht in:	Journal of biomechanics 2019-01, Vol.83, p.273-279
Hauptverfasser:	Sampson, Sara L., Sylvia, Meghan, Fields, Aaron J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aging Biological Transport Biomechanical Phenomena Biotransport Cadavers Cartilage Cartilage - metabolism Cartilage - physiology Cartilage endplate Convection Degeneration Dextran Dynamic loading Flow resistance Fluid dynamics Fluid flow Fluorescein High resistance Humans Hydration Intervertebral Disc - metabolism Intervertebral Disc - physiology Intervertebral disc degeneration Intervertebral discs Load Mechanical loading Middle Aged Nutrition Porosity Simulation Sodium Solutes Spine Transport Weight-Bearing
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