Circadian protein CLK suppresses transforming growth factor-β expression in peripheral B cells of nurses with day-night shift rotation

The mechanism of dysfunction of regulatory B cells is unclear. The circadian locomotor output cycles kaput (CLK) regulates immune responses. CLK expression can be increased by alteration of the circadian rhythm. This study tests a hypothesis that alteration of the circadian rhythm, such as engaging...

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Veröffentlicht in:	American journal of translational research 2018-01, Vol.10 (12), p.4331-4337
Hauptverfasser:	Yang, Hui, Yang, Li-Tao, Liu, Jun, Tang, Shan, Zhao, Xiulan, Wang, Qiaohong, Zhang, Shaoguo, Shi, Meixia, Pan, Wei, Yang, Ping-Chang
Format:	Artikel
Sprache:	eng
Schlagworte:	Original
Online-Zugang:	Volltext
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