Epigenetic Targeting of Autophagy via HDAC Inhibition in Tumor Cells: Role of p53

Tumor development and progression is the consequence of genetic as well as epigenetic alterations of the cell. As part of the epigenetic regulatory system, histone acetyltransferases (HATs) and deacetylases (HDACs) drive the modification of histone as well as non-histone proteins. Derailed acetylati...

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Veröffentlicht in:International journal of molecular sciences 2018-12, Vol.19 (12), p.3952
Hauptverfasser: Mrakovcic, Maria, Bohner, Lauren, Hanisch, Marcel, Fröhlich, Leopold F
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Sprache:eng
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