Simultaneous hyperthermia‐chemotherapy effect by arterial injection of Fe(Salen) for femur tumor

We previously identified a novel nanomagnetic particle, N,N′‐bis(salicylidene)ethylenediamine iron [Fe(Salen)]. Fe(Salen) not only shows antitumor effects but also magnetic properties. We found that Fe(Salen) can be used for magnet‐guided drug delivery and visualization of accumulated drug by magnet...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer science 2019-01, Vol.110 (1), p.356-365
Hauptverfasser:	Umemura, Masanari, Islam, Md. Rafikul, Fukumura, Hidenobu, Sato, Itaru, Kawabata, Yusuke, Matsuo, Kousuke, Nakakaji, Rina, Nagasako, Akane, Ohtake, Makoto, Takayuki, Fujita, Yokoyama, Utako, Nakayama, Tomohiro, Eguchi, Haruki, Ishikawa, Yoshihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	alternating current magnetic field Animals Antitumor activity Apoptosis arterial injection Cancer therapies Carcinoma, Squamous Cell - therapy Catheters Cell growth Cell Line, Tumor Cell Survival - drug effects Chemotherapy Cytotoxicity Drug delivery Drug Delivery Systems - methods Drug dosages Fe(Salen) Femoral Neoplasms - therapy Femur femur tumor Fever Humans Hyperthermia Hyperthermia, Induced - methods Injection Injections, Intra-Arterial Injections, Intravenous Iron Compounds - administration & dosage Iron Compounds - pharmacology Laboratory animals Magnetic Fields Magnetic properties Magnetic resonance imaging Male Methotrexate Methotrexate - administration & dosage Methotrexate - pharmacology Nanoparticles Nanoparticles - administration & dosage NMR Nuclear magnetic resonance Original Rabbits Rats, Sprague-Dawley Squamous cell carcinoma Toxicity Tumors Veins & arteries Xenograft Model Antitumor Assays
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!