CRISPR/Cas9-mediated kif15 mutations accelerate axonal outgrowth during neuronal development and regeneration in zebrafish

KIF15, the vertebrate kinesin-12, is best known as a mitotic motor protein, but continues to be expressed in neurons. Like KIF11 (the vertebrate kinesin-5), KIF15 interacts with microtubules in the axon to limit their sliding relative to one another. Unlike KIF11, KIF15 also regulates interactions b...

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Veröffentlicht in:	Traffic (Copenhagen, Denmark) Denmark), 2018-11, Vol.20 (1), p.71-81
Hauptverfasser:	Dong, Zhangji, Wu, Shuwen, Zhu, Chenwen, Wang, Xueting, Li, Yuanyuan, Chen, Xu, Liu, Dong, Qiang, Liang, Baas, Peter W., Liu, Mei
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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