ZNF445 is a primary regulator of genomic imprinting

Genomic imprinting is an epigenetic process regulated by germline-derived DNA methylation, causing parental origin-specific monoallelic gene expression. Zinc finger protein 57 (ZFP57) is critical for maintenance of this epigenetic memory during post-fertilization reprogramming, yet incomplete penetr...

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Veröffentlicht in:	Genes & development 2019-01, Vol.33 (1-2), p.49-54
Hauptverfasser:	Takahashi, Nozomi, Coluccio, Andrea, Thorball, Christian W, Planet, Evarist, Shi, Hui, Offner, Sandra, Turelli, Priscilla, Imbeault, Michael, Ferguson-Smith, Anne C, Trono, Didier
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells, Cultured Conserved Sequence DNA Methylation - genetics Embryonic Stem Cells Genomic Imprinting - genetics HEK293 Cells Humans Kruppel-Like Transcription Factors - genetics Kruppel-Like Transcription Factors - metabolism Mice Mice, Inbred C57BL Repressor Proteins Research Communication Transcription Factors - genetics Transcription Factors - metabolism
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