Evolving imprinting control regions: KRAB zinc fingers hold the key

The monoallelic parent of origin-specific expression of imprinted genes in mammals is regulated by differentially DNA methylated imprinting control regions (ICRs). In contrast to most of the genome, ICRs must maintain their DNA methylation and parental identity despite extensive epigenetic reprogram...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Genes & development 2019-01, Vol.33 (1-2), p.1-3
Hauptverfasser:	Juan, Aimee M, Bartolomei, Marisa S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals DNA Methylation DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Epigenomics Genomic Imprinting - genetics Humans Mice Outlook Zinc Fingers
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!