Predictive value of angiogenic proteins in patients with metastatic melanoma treated with bevacizumab monotherapy

The incidence of malignant melanoma is rising worldwide and survival for metastatic disease is still poor. Recently, new treatment options have become available. Still, predictive biomarkers are needed to optimise treatment for this patient group. In this study, we investigated the predictive value...

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Veröffentlicht in:	The journal of pathology. Clinical research 2019-01, Vol.5 (1), p.53-62
Hauptverfasser:	Schuster, Cornelia, Akslen, Lars A, Stokowy, Tomasz, Straume, Oddbjørn
Format:	Artikel
Sprache:	eng
Schlagworte:	Activin Activin A Angiogenesis Bevacizumab bevacizumab monotherapy Biomarkers Chemotherapy Disease control Grants IL1β Immunohistochemistry Immunotherapy Melanoma Metastases Metastasis metastatic melanoma Microvasculature Monoclonal antibodies Original Ovarian cancer paraffin embedded tissue Patients predictive marker Protein arrays Protein expression Proteins serum Skin cancer Studies Targeted cancer therapy Tumors U-Plasminogen activator uPAR Vascular endothelial growth factor
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