Reward and executive control network resting-state functional connectivity is associated with impulsivity during reward-based decision making for cocaine users

•Functional changes in reward and executive brain circuitry occur in addiction.•Resting-state connectivity was related to risk-taking propensity for cocaine users.•Resting-state connectivity was related to delay discounting for controls. Cocaine addiction is related to impulsive decision making that...

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Veröffentlicht in:	Drug and alcohol dependence 2019-01, Vol.194, p.32-39
Hauptverfasser:	Hobkirk, Andréa L., Bell, Ryan P., Utevsky, Amanda V., Huettel, Scott, Meade, Christina S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Addictions Adult Brain Brain - diagnostic imaging Brain - physiopathology Brain mapping Brain Mapping - methods Brain research Circuits Clinical decision making Cocaine Cocaine - adverse effects Cocaine-Related Disorders - diagnostic imaging Cocaine-Related Disorders - physiopathology Cognition Cognitive ability Computerization Connectivity Decision making Decision Making - drug effects Decision Making - physiology Drug abuse Drug addiction Executive control Executive function Executive Function - drug effects Executive Function - physiology Female fMRI Functional connectivity Functional magnetic resonance imaging Functionals Humans Imbalance Impulsive behavior Impulsive Behavior - drug effects Impulsive Behavior - physiology Impulsivity Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Moderation Narcotics Neostriatum Nerve Net - diagnostic imaging Nerve Net - drug effects Nerve Net - physiology Networks Neural networks Neuroimaging Questionnaires Regression analysis Reinforcement Resting Resting state Reward Salience
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