Exogenous Hydrogen Sulfide Supplement Attenuates Isoproterenol-Induced Myocardial Hypertrophy in a Sirtuin 3-Dependent Manner

Hydrogen sulfide (H2S) is a gasotransmitter with a variety of cardiovascular protective effects. Sirtuin 3 (SIRT3) is closely related to mitochondrial function and oxidative stress. We found that NaHS increased SIRT3 expression in the preventive effect on isoproterenol- (ISO-) induced myocardial hyp...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2018-01, Vol.2018 (2018), p.1-17
Hauptverfasser:	Meng, Guoliang, Wang, Yuqin, Sun, Linlin, Xu, Mengting, Liu, Lulu, Chen, Yun, Yu, Jin, Zhang, Jingyao, Luo, Huiqin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Atherosclerosis Biology Blood pressure Cardiac glycosides Cardiomegaly - chemically induced Cardiomegaly - pathology Cardiotonic agents Heart Heart failure Humans Hydrogen sulfide Hydrogen Sulfide - metabolism Hydrogen Sulfide - pharmacology Hydrogen Sulfide - therapeutic use Hypertrophy Isoproterenol - adverse effects Laboratory animals Male Medical research Mice Mice, Inbred C57BL Myocardium - pathology Natriuretic peptides Oxidation Oxidative stress Physiology Plasma Proteins RNA Sirtuin 3 - metabolism Superoxide Utrophin
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