How does the promoter of an oocyte-specific gene function in male germ cells?
Studying gene expression in germ cells is useful for elucidating mechanisms of transcriptional regulation, because different genes are activated in male and female germ cells. The promoter regions of an oocyte-specific gene, Oog1, have been characterized. Driving the expression of green fluorescent...
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| Veröffentlicht in: | Journal of Reproduction and Development 2018, Vol.64(6), pp.463-468 |
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| container_title | Journal of Reproduction and Development |
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| creator | MIKI, Yuka TSUKAMOTO, Satoshi MINAMI, Naojiro |
| description | Studying gene expression in germ cells is useful for elucidating mechanisms of transcriptional regulation, because different genes are activated in male and female germ cells. The promoter regions of an oocyte-specific gene, Oog1, have been characterized. Driving the expression of green fluorescent protein with these different promoter regions provided us with critical information on the regulation of gene expression. The 3.9 kb long promoter functions in both male and female germ cells in transgenic mice. What is the cause of this sexually dimorphic expression? There may be important factors within and perhaps also outside this 3.9 kb promoter region that are required to maintain proper sex-specific gene expression. |
| doi_str_mv | 10.1262/jrd.2018-060 |
| format | Article |
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The promoter regions of an oocyte-specific gene, Oog1, have been characterized. Driving the expression of green fluorescent protein with these different promoter regions provided us with critical information on the regulation of gene expression. The 3.9 kb long promoter functions in both male and female germ cells in transgenic mice. What is the cause of this sexually dimorphic expression? There may be important factors within and perhaps also outside this 3.9 kb promoter region that are required to maintain proper sex-specific gene expression.</description><identifier>ISSN: 0916-8818</identifier><identifier>EISSN: 1348-4400</identifier><identifier>DOI: 10.1262/jrd.2018-060</identifier><identifier>PMID: 30197401</identifier><language>eng</language><publisher>Japan: THE SOCIETY FOR REPRODUCTION AND DEVELOPMENT</publisher><subject>DNA methylation ; Epigenetics ; Gene expression ; Gene regulation ; Germ cells ; Green fluorescent protein ; Oocyte ; Opinions and Hypotheses ; Promoter ; Sexual dimorphism ; Transcription ; Transgenic mice</subject><ispartof>Journal of Reproduction and Development, 2018, Vol.64(6), pp.463-468</ispartof><rights>2018 Society for Reproduction and Development</rights><rights>Copyright Japan Science and Technology Agency 2018</rights><rights>2018 Society for Reproduction and Development 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c509t-a24c9be008bc829606df7f8fbfa8fdb01068df470709cf4b4e6d907b2deca2e43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305850/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305850/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,1877,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30197401$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MIKI, Yuka</creatorcontrib><creatorcontrib>TSUKAMOTO, Satoshi</creatorcontrib><creatorcontrib>MINAMI, Naojiro</creatorcontrib><title>How does the promoter of an oocyte-specific gene function in male germ cells?</title><title>Journal of Reproduction and Development</title><addtitle>J. Reprod. Dev.</addtitle><description>Studying gene expression in germ cells is useful for elucidating mechanisms of transcriptional regulation, because different genes are activated in male and female germ cells. The promoter regions of an oocyte-specific gene, Oog1, have been characterized. Driving the expression of green fluorescent protein with these different promoter regions provided us with critical information on the regulation of gene expression. The 3.9 kb long promoter functions in both male and female germ cells in transgenic mice. What is the cause of this sexually dimorphic expression? There may be important factors within and perhaps also outside this 3.9 kb promoter region that are required to maintain proper sex-specific gene expression.</description><subject>DNA methylation</subject><subject>Epigenetics</subject><subject>Gene expression</subject><subject>Gene regulation</subject><subject>Germ cells</subject><subject>Green fluorescent protein</subject><subject>Oocyte</subject><subject>Opinions and Hypotheses</subject><subject>Promoter</subject><subject>Sexual dimorphism</subject><subject>Transcription</subject><subject>Transgenic mice</subject><issn>0916-8818</issn><issn>1348-4400</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNpVkM9P5CAUgMlGo6Prbc-GxKvVB2UovexGjb8SjZfdM6H0MdNJCyMwGv97Ozs60QskvC8fLx8hvxicMS75-SK2ZxyYKkDCDzJhpVCFEAA7ZAI1k4VSTO2Tg5QWACWfSrFH9ktgdSWATcjjXXilbcBE8xzpMoYhZIw0OGo8DcG-ZSzSEm3nOktn6JG6lbe5C552ng6mx_E1DtRi36c_P8muM33Co4_7kPy7uf57dVc8PN3eX108FHYKdS4MF7ZuEEA1VvFagmxd5ZRrnFGubYCBVK0TFVRQWycagbKtoWp4i9ZwFOUh-b3xLlfNgK1Fn6Pp9TJ2g4lvOphOf5_4bq5n4UXLEqZqCqPg5EMQw_MKU9aLsIp-3FlzXtaSl8DZSJ1uKBtDShHd9gcGeh1fj_H1Or4e44_48dettvBn7RG43ACLlM0Mt4CJubM9_rdJoeX6-LRuh3ZuokZfvgO8P5it</recordid><startdate>20180101</startdate><enddate>20180101</enddate><creator>MIKI, Yuka</creator><creator>TSUKAMOTO, Satoshi</creator><creator>MINAMI, Naojiro</creator><general>THE SOCIETY FOR REPRODUCTION AND DEVELOPMENT</general><general>Japan Science and Technology Agency</general><general>The Society for Reproduction and Development</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>5PM</scope></search><sort><creationdate>20180101</creationdate><title>How does the promoter of an oocyte-specific gene function in male germ cells?</title><author>MIKI, Yuka ; TSUKAMOTO, Satoshi ; MINAMI, Naojiro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c509t-a24c9be008bc829606df7f8fbfa8fdb01068df470709cf4b4e6d907b2deca2e43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>DNA methylation</topic><topic>Epigenetics</topic><topic>Gene expression</topic><topic>Gene regulation</topic><topic>Germ cells</topic><topic>Green fluorescent protein</topic><topic>Oocyte</topic><topic>Opinions and Hypotheses</topic><topic>Promoter</topic><topic>Sexual dimorphism</topic><topic>Transcription</topic><topic>Transgenic mice</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MIKI, Yuka</creatorcontrib><creatorcontrib>TSUKAMOTO, Satoshi</creatorcontrib><creatorcontrib>MINAMI, Naojiro</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of Reproduction and Development</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MIKI, Yuka</au><au>TSUKAMOTO, Satoshi</au><au>MINAMI, Naojiro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>How does the promoter of an oocyte-specific gene function in male germ cells?</atitle><jtitle>Journal of Reproduction and Development</jtitle><addtitle>J. Reprod. Dev.</addtitle><date>2018-01-01</date><risdate>2018</risdate><volume>64</volume><issue>6</issue><spage>463</spage><epage>468</epage><pages>463-468</pages><issn>0916-8818</issn><eissn>1348-4400</eissn><abstract>Studying gene expression in germ cells is useful for elucidating mechanisms of transcriptional regulation, because different genes are activated in male and female germ cells. The promoter regions of an oocyte-specific gene, Oog1, have been characterized. Driving the expression of green fluorescent protein with these different promoter regions provided us with critical information on the regulation of gene expression. The 3.9 kb long promoter functions in both male and female germ cells in transgenic mice. What is the cause of this sexually dimorphic expression? 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| identifier | ISSN: 0916-8818 |
| ispartof | Journal of Reproduction and Development, 2018, Vol.64(6), pp.463-468 |
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| language | eng |
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| source | DOAJ Directory of Open Access Journals; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; PubMed Central Open Access |
| subjects | DNA methylation Epigenetics Gene expression Gene regulation Germ cells Green fluorescent protein Oocyte Opinions and Hypotheses Promoter Sexual dimorphism Transcription Transgenic mice |
| title | How does the promoter of an oocyte-specific gene function in male germ cells? |
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