Perivascular Adventitial Fibroblast Specialization Accompanies T Cell Retention in the Inflamed Human Dermis

Perivascular accumulation of lymphocytes can be a prominent histopathologic feature of various human inflammatory skin diseases. Select examples include systemic sclerosis, spongiotic dermatitis, and cutaneous lupus. Although a large body of work has described various aspects of the endothelial and...

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Veröffentlicht in:	The Journal of immunology (1950) 2019-01, Vol.202 (1), p.56-68
Hauptverfasser:	Barron, Alexander M S, Mantero, Julio C, Ho, Jonathan D, Nazari, Banafsheh, Horback, Katharine L, Bhawan, Jag, Lafyatis, Robert, Lam, Christina, Browning, Jeffrey L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Cells, Cultured Clinical and Human Immunology Dermatitis - immunology Female Fibroblasts - physiology Humans Inflammation - immunology Lupus Erythematosus, Discoid - immunology Male Middle Aged Scleroderma, Systemic - immunology Skin - immunology T-Lymphocytes - immunology Thy-1 Antigens - metabolism Vascular Cell Adhesion Molecule-1 - metabolism Young Adult
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