Gut microbiota dysbiosis and diarrhea in kidney transplant recipients

Posttransplant diarrhea is associated with kidney allograft failure and death, but its etiology remains unknown in the majority of cases. Because altered gut microbial ecology is a potential basis for diarrhea, we investigated whether posttransplant diarrhea is associated with gut dysbiosis. We enro...

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Veröffentlicht in:	American journal of transplantation 2019-02, Vol.19 (2), p.488-500
Hauptverfasser:	Lee, John Richard, Magruder, Matthew, Zhang, Lisa, Westblade, Lars F., Satlin, Michael J., Robertson, Amy, Edusei, Emmanuel, Crawford, Carl, Ling, Lilan, Taur, Ying, Schluter, Jonas, Lubetzky, Michelle, Dadhania, Darshana, Pamer, Eric, Suthanthiran, Manikkam
Format:	Artikel
Sprache:	eng
Schlagworte:	Abundance Adult Bacteria - genetics Bacteria - growth & development Bacteria - isolation & purification Case-Control Studies Cohort Studies complication: medical/metabolic Diarrhea Diarrhea - etiology Diarrhea - pathology Digestive system Dysbacteriosis Dysbiosis - etiology Dysbiosis - pathology Etiology Feces Feces - microbiology Female Follow-Up Studies Gastrointestinal Microbiome Gastrointestinal tract Glomerular Filtration Rate Graft Rejection - etiology Graft Rejection - pathology Graft Survival gut microbiota Humans Intestinal microflora kidney disease Kidney diseases Kidney Failure, Chronic - surgery Kidney Function Tests Kidney transplantation Kidney Transplantation - adverse effects kidney transplantation/nephrology Kidney transplants Male microbiomics Microbiota Middle Aged Pathogens Phylogeny Polymerase chain reaction Postoperative Complications Prognosis Protozoa Renal failure Risk Factors RNA, Ribosomal, 16S - genetics rRNA 16S translational research/science Transplants & implants
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