Discovery of Kaposi’s sarcoma herpesvirus-encoded circular RNAs and a human antiviral circular RNA

Noncoding RNAs have substantial effects in host–virus interactions. Circular RNAs (circRNAs) are novel single-stranded noncoding RNAs which can decoy other RNAs or RNA-binding proteins to inhibit their functions. The role of circRNAs is largely unknown in the context of Kaposi’s sarcoma herpesvirus...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2018-12, Vol.115 (50), p.12805-12810
Hauptverfasser:	Tagawa, Takanobu, Gao, Shaojian, Koparde, Vishal N., Gonzalez, Mileidy, Spouge, John L., Serquiña, Anna P., Lurain, Kathryn, Ramaswami, Ramya, Uldrick, Thomas S., Yarchoan, Robert, Ziegelbauer, Joseph M.
Format:	Artikel
Sprache:	eng
Schlagworte:	B-Lymphocytes - virology Biological Sciences Castleman Disease - genetics Castleman Disease - virology Cell Line Circular RNA Circularity Ectopic expression Effusion Endothelial cells Endothelial Cells - virology Gene expression Gene Expression Profiling - methods Gene Expression Regulation, Viral - genetics Genes, Viral - genetics Genomes HEK293 Cells Herpes viruses Herpesvirus 8, Human - genetics Human Umbilical Vein Endothelial Cells Humans Kaposis sarcoma Lymph nodes Lymphocytes B Lymphoma Lymphoma, Primary Effusion - genetics Lymphoma, Primary Effusion - virology MicroRNAs - genetics miRNA Open Reading Frames - genetics Primary effusion lymphoma Primers Proteins Ribonuclease Ribonucleic acid RNA RNA - genetics RNA, Circular RNA, Viral - genetics RNA-binding protein Sarcoma Sarcoma, Kaposi - genetics Sarcoma, Kaposi - virology Viruses
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