A large primary orbital lymphoma with proptosis: A case report and review
Background: Primary orbital lymphomas are a rare subset of tumors constituting 1-2% of non-Hodgkin's lymphoma. They are mostly indolent B-cell lymphomas presenting with gradual progressive proptosis, decreased visual acuity, restricted ocular mobility, and diplopia. The role of surgery is mainl...
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| Veröffentlicht in: | Surgical neurology international 2018-01, Vol.9 (1), p.249-249 |
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| description | Background: Primary orbital lymphomas are a rare subset of tumors constituting 1-2% of non-Hodgkin's lymphoma. They are mostly indolent B-cell lymphomas presenting with gradual progressive proptosis, decreased visual acuity, restricted ocular mobility, and diplopia. The role of surgery is mainly for obtaining a biopsy. Most of these tumors require multimodality treatment including chemotherapy, radiation, or both, which have major role.
Case Description: We report one such case of marginal zone lymphoma of the orbit in a female with significant proptosis who was treated with multimodality treatment, including surgical excision as a major treatment modality. Decompression of symptomatic proptosis was followed by chemotherapy and radiation.
Conclusion: Primary orbital lymphoma is a rare clinical entity with diverse clinical outcomes. It can be successfully managed with surgical excision for decompression of mechanical proptosis followed by chemotherapy, radiation, or both. |
| doi_str_mv | 10.4103/SNI.SNI_270_18 |
| format | Article |
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Case Description: We report one such case of marginal zone lymphoma of the orbit in a female with significant proptosis who was treated with multimodality treatment, including surgical excision as a major treatment modality. Decompression of symptomatic proptosis was followed by chemotherapy and radiation.
Conclusion: Primary orbital lymphoma is a rare clinical entity with diverse clinical outcomes. It can be successfully managed with surgical excision for decompression of mechanical proptosis followed by chemotherapy, radiation, or both.</description><identifier>ISSN: 2152-7806</identifier><identifier>ISSN: 2229-5097</identifier><identifier>EISSN: 2152-7806</identifier><identifier>DOI: 10.4103/SNI.SNI_270_18</identifier><identifier>PMID: 30603233</identifier><language>eng</language><publisher>United States: Wolters Kluwer India Pvt. Ltd</publisher><subject>Case reports ; Chemotherapy ; Eye movements ; General Neurosurgery: Case Report ; Lymphoma ; NMR ; Nuclear magnetic resonance ; Patients ; Radiation therapy ; Surgery ; Tumors</subject><ispartof>Surgical neurology international, 2018-01, Vol.9 (1), p.249-249</ispartof><rights>2018. This work is published under https://creativecommons.org/licenses/by-nc-sa/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright: © 2018 Surgical Neurology International 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c381a-29623fc8871f92ea2e1446be3348eb502fc4f9b19de48043d146a786585fb5663</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293602/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293602/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30603233$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Borkar, Ashwin</creatorcontrib><creatorcontrib>Jain, Kapil</creatorcontrib><creatorcontrib>Jain, Vijendra</creatorcontrib><title>A large primary orbital lymphoma with proptosis: A case report and review</title><title>Surgical neurology international</title><addtitle>Surg Neurol Int</addtitle><description>Background: Primary orbital lymphomas are a rare subset of tumors constituting 1-2% of non-Hodgkin's lymphoma. They are mostly indolent B-cell lymphomas presenting with gradual progressive proptosis, decreased visual acuity, restricted ocular mobility, and diplopia. The role of surgery is mainly for obtaining a biopsy. Most of these tumors require multimodality treatment including chemotherapy, radiation, or both, which have major role.
Case Description: We report one such case of marginal zone lymphoma of the orbit in a female with significant proptosis who was treated with multimodality treatment, including surgical excision as a major treatment modality. Decompression of symptomatic proptosis was followed by chemotherapy and radiation.
Conclusion: Primary orbital lymphoma is a rare clinical entity with diverse clinical outcomes. It can be successfully managed with surgical excision for decompression of mechanical proptosis followed by chemotherapy, radiation, or both.</description><subject>Case reports</subject><subject>Chemotherapy</subject><subject>Eye movements</subject><subject>General Neurosurgery: Case Report</subject><subject>Lymphoma</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Patients</subject><subject>Radiation therapy</subject><subject>Surgery</subject><subject>Tumors</subject><issn>2152-7806</issn><issn>2229-5097</issn><issn>2152-7806</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp1UV1LwzAUDaI4mXv1UQI-b-araeqDMIYfg6EPKvgW0jbdunVNTbqV_Xvjus35YOCSC_fk3JNzALjCaMAwordvL-OBL0lCJLE4ARcEB6QfCsRPj_oO6Dk3R_5QijGKzkGHIo4oofQCjIewUHaqYWXzpbIbaGyc16qAxWZZzcxSwSavZ35qqtq43N3BIUyU09DqytgaqjL17TrXzSU4y1ThdG93d8HH48P76Lk_eX0aj4aTfkIFVn0ScUKzRIgQZxHRimjMGI81pUzoOEAkS1gWxThKNROI0RQzrkLBAxFkccA57YL7lrdaxUudJrqsrSrkTr80Kpd_J2U-k1OzlpxElCPiCW52BNZ8rbSr5dysbOk1S4K5QCIgYeBRgxaVWOOc1dlhA0byx33pynxbrfv-wfWxrgN877UHfLaAxhS1tm5RrBptpccuStP8QysJi-RQbjP6_WObkdxnRL8BcQKhqQ</recordid><startdate>20180101</startdate><enddate>20180101</enddate><creator>Borkar, Ashwin</creator><creator>Jain, Kapil</creator><creator>Jain, Vijendra</creator><general>Wolters Kluwer India Pvt. 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They are mostly indolent B-cell lymphomas presenting with gradual progressive proptosis, decreased visual acuity, restricted ocular mobility, and diplopia. The role of surgery is mainly for obtaining a biopsy. Most of these tumors require multimodality treatment including chemotherapy, radiation, or both, which have major role.
Case Description: We report one such case of marginal zone lymphoma of the orbit in a female with significant proptosis who was treated with multimodality treatment, including surgical excision as a major treatment modality. Decompression of symptomatic proptosis was followed by chemotherapy and radiation.
Conclusion: Primary orbital lymphoma is a rare clinical entity with diverse clinical outcomes. It can be successfully managed with surgical excision for decompression of mechanical proptosis followed by chemotherapy, radiation, or both.</abstract><cop>United States</cop><pub>Wolters Kluwer India Pvt. Ltd</pub><pmid>30603233</pmid><doi>10.4103/SNI.SNI_270_18</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Case reports Chemotherapy Eye movements General Neurosurgery: Case Report Lymphoma NMR Nuclear magnetic resonance Patients Radiation therapy Surgery Tumors |
| title | A large primary orbital lymphoma with proptosis: A case report and review |
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