Multiparametric MRI detects longitudinal evolution of folic acid-induced nephropathy in mice

The rodent model of folic acid (FA)-induced acute kidney injury (AKI) provides a useful model for studying human AKI, but little is known about longitudinal changes in renal hemodynamics and evolution of renal fibrosis in vivo. In this work, we aimed to longitudinally assess renal structural and fun...

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Veröffentlicht in:	American journal of physiology. Renal physiology 2018-11, Vol.315 (5), p.F1252-F1260
Hauptverfasser:	Jiang, Kai, Ponzo, Tristan A, Tang, Hui, Mishra, Prasanna K, Macura, Slobodan I, Lerman, Lilach O
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury - chemically induced Acute Kidney Injury - diagnostic imaging Acute Kidney Injury - pathology Acute Kidney Injury - physiopathology Animals Disease Models, Animal Disease Progression Fibrosis Folic Acid Glomerular Filtration Rate Hemodynamics Hypoxia Kidney - diagnostic imaging Kidney - pathology Kidney - physiopathology Kidneys Magnetic Resonance Imaging Male Mice, Inbred C57BL Necrosis Nephropathy NMR Nuclear magnetic resonance Organ Size Oxygenation Perfusion Predictive Value of Tests Renal Circulation Rodents Structure-function relationships Time Factors Vitamin B
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