Phenytoin‐induced choreoathetosis after serial seizures due to traumatic brain injury and chronic alcoholism

Key Clinical Message Intravenous phenytoin (PHT) for suspected seizures may trigger severe choreoathetosis. Discontinuation of PHT results in immediate and complete resolution of hyperkinesias. Co‐medication with valproic acid, levetiracetam, tranquilisers, and anesthetics or alcohol presumably do n...

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Veröffentlicht in:Clinical case reports 2018-12, Vol.6 (12), p.2316-2318
Hauptverfasser: Finsterer, Josef, Keller, Hans, Reining‐Festa, Alice, Enzelsberger, Barbara, Weidinger, Franz
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container_end_page 2318
container_issue 12
container_start_page 2316
container_title Clinical case reports
container_volume 6
creator Finsterer, Josef
Keller, Hans
Reining‐Festa, Alice
Enzelsberger, Barbara
Weidinger, Franz
description Key Clinical Message Intravenous phenytoin (PHT) for suspected seizures may trigger severe choreoathetosis. Discontinuation of PHT results in immediate and complete resolution of hyperkinesias. Co‐medication with valproic acid, levetiracetam, tranquilisers, and anesthetics or alcohol presumably do not modify this adverse effect of PHT. Choreoathetosis can be easily misinterpreted as seizures. Intravenous phenytoin (PHT) for suspected seizures may trigger severe choreoathetosis. Discontinuation of PHT results in immediate and complete resolution of hyperkinesias. Co‐medication with valproic acid, levetiracetam, tranquilisers, and anesthetics or alcohol presumably do not modify this adverse effect of PHT. Choreoathetosis can be easily misinterpreted as seizures.
doi_str_mv 10.1002/ccr3.1870
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source Wiley Online Library Open Access; DOAJ Directory of Open Access Journals; Wiley Online Library Journals Frontfile Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central
subjects antiepileptic drugs
Case Report
Case Reports
diphenyl‐hydantoin
epilepsy
movement disorder
side effects
title Phenytoin‐induced choreoathetosis after serial seizures due to traumatic brain injury and chronic alcoholism
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