Robust increases in erythropoietin production by the hypoxic fetus is a response to protect the brain and other vital organs

Fetal erythropoietin (EPO), in addition to regulating erythropoiesis, has also tissue-protective properties based on its anti-inflammatory, anti-apoptotic, antioxidant, and neurotrophic effects. Notably, EPO concentrations needed for tissue protection are 100–1000 times higher than concentrations ne...

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Veröffentlicht in:Pediatric research 2018-12, Vol.84 (6), p.807-812
Hauptverfasser: Teramo, Kari A., Klemetti, Miira M., Widness, John A.
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Sprache:eng
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