CD133 Expression in Glioblastoma Multiforme: A Literature Review
Glioblastoma, also known as glioblastoma multiforme (GBM), is the most common primary brain tumor. Extensive research has been carried out to discover the factors associated with the course and progression of GBM. CD133 is a glycoprotein antigen found in normal and malignant tissues. CD133 has been...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2018-10, Vol.10 (10), p.e3439-e3439 |
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| container_title | Curēus (Palo Alto, CA) |
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| creator | Ahmed, Syed Ijlal Javed, Gohar Laghari, Altaf Ali Bareeqa, Syeda Beenish Farrukh, Saba Zahid, Shajeeah Samar, Syeda Sana Aziz, Kashif |
| description | Glioblastoma, also known as glioblastoma multiforme (GBM), is the most common primary brain tumor. Extensive research has been carried out to discover the factors associated with the course and progression of GBM. CD133 is a glycoprotein antigen found in normal and malignant tissues. CD133 has been recognized as a marker for the growth of cancer cells. The association between this tissue marker and GBM is being investigated. The aim of this review was to evaluate the role of CD133 as a tumor marker for the prognosis of GBM. |
| doi_str_mv | 10.7759/cureus.3439 |
| format | Article |
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Extensive research has been carried out to discover the factors associated with the course and progression of GBM. CD133 is a glycoprotein antigen found in normal and malignant tissues. CD133 has been recognized as a marker for the growth of cancer cells. The association between this tissue marker and GBM is being investigated. The aim of this review was to evaluate the role of CD133 as a tumor marker for the prognosis of GBM.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.3439</identifier><identifier>PMID: 30555755</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Age ; Antigens ; Apoptosis ; Biomarkers ; Brain cancer ; Brain research ; Gene expression ; Internal medicine ; Literature reviews ; Medical prognosis ; Medicine ; Metastasis ; Neurosurgery ; Oncology ; Stem cells ; Tumorigenesis ; Tumors</subject><ispartof>Curēus (Palo Alto, CA), 2018-10, Vol.10 (10), p.e3439-e3439</ispartof><rights>Copyright © 2018, Ahmed et al. This work is published under http://creativecommons.org/licenses/by/3.0/ (the “License”). 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| source | PubMed Central Open Access; PubMed Central |
| subjects | Age Antigens Apoptosis Biomarkers Brain cancer Brain research Gene expression Internal medicine Literature reviews Medical prognosis Medicine Metastasis Neurosurgery Oncology Stem cells Tumorigenesis Tumors |
| title | CD133 Expression in Glioblastoma Multiforme: A Literature Review |
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