CD133 Expression in Glioblastoma Multiforme: A Literature Review

CD133 Expression in Glioblastoma Multiforme: A Literature Review

Glioblastoma, also known as glioblastoma multiforme (GBM), is the most common primary brain tumor. Extensive research has been carried out to discover the factors associated with the course and progression of GBM. CD133 is a glycoprotein antigen found in normal and malignant tissues. CD133 has been...

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Veröffentlicht in:Curēus (Palo Alto, CA) CA), 2018-10, Vol.10 (10), p.e3439-e3439
Hauptverfasser: Ahmed, Syed Ijlal, Javed, Gohar, Laghari, Altaf Ali, Bareeqa, Syeda Beenish, Farrukh, Saba, Zahid, Shajeeah, Samar, Syeda Sana, Aziz, Kashif
Format: Artikel
Sprache:eng
Schlagworte:
Age
Antigens
Apoptosis
Biomarkers
Brain cancer
Brain research
Gene expression
Internal medicine
Literature reviews
Medical prognosis
Medicine
Metastasis
Neurosurgery
Oncology
Stem cells
Tumorigenesis
Tumors
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Zusammenfassung:Glioblastoma, also known as glioblastoma multiforme (GBM), is the most common primary brain tumor. Extensive research has been carried out to discover the factors associated with the course and progression of GBM. CD133 is a glycoprotein antigen found in normal and malignant tissues. CD133 has been recognized as a marker for the growth of cancer cells. The association between this tissue marker and GBM is being investigated. The aim of this review was to evaluate the role of CD133 as a tumor marker for the prognosis of GBM.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.3439