Comparative Secretome Analyses of Primary Murine White and Brown Adipocytes Reveal Novel Adipokines

The secretome of white and brown primary murine adipocytes, with and without stimulation with norepinephrine (NE), has been determined by using mass spectrometry combined with AHA labeling and pulsed SILAC. The results reported reveal a comprehensive catalogue of novel adipokines secreted from white...

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Veröffentlicht in:	Molecular & cellular proteomics 2018-12, Vol.17 (12), p.2358-2370
Hauptverfasser:	Ali Khan, Asrar, Hansson, Jenny, Weber, Peter, Foehr, Sophia, Krijgsveld, Jeroen, Herzig, Stephan, Scheideler, Marcel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes, Brown - metabolism Adipocytes, White - metabolism Adipokines - analysis Adipokines - biosynthesis Adipose Tissue, Brown - metabolism Adipose Tissue, White - metabolism Adrenergic stimulation Animals Brown adipocytes Carbohydrate Metabolism Cell Death Cell secretion Cells, Cultured Chromatography, Liquid Leptin - analysis Linear Models Male Mass spectrometry Mice Mice, Inbred C57BL Molecular biology Murine SVF cells Norepinephrine - pharmacology Omics Oxidation-Reduction Resistin - analysis Secretome Secretory Pathway - physiology SILAC Tandem Mass Spectrometry White adipocytes
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