Dynamic Core–Shell Bioconjugates for Targeted Protein Delivery and Release

Dynamic covalent chemistry is a versatile and powerful tool that integrates both stable chemical bonds and stimulus responsiveness into the construction of smart biotherapeutics. With minimalistic molecular design, a dynamic covalent protein assembly that incorporates selective targeting and intrace...

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Veröffentlicht in:	Chemistry, an Asian journal an Asian journal, 2018-11, Vol.13 (22), p.3474-3479
Hauptverfasser:	Seidler, Christiane, Zegota, Maksymilian Marek, Raabe, Marco, Kuan, Seah Ling, Ng, David Y. W., Weil, Tanja
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 Cells Assembly bioconjugates boronic acid Boronic Acids - chemistry Calcium - metabolism Chemical bonds Chemistry Communication Communications Cytochromes Cytochromes c - chemistry Cytochromes c - metabolism dynamic covalent chemistry Fluorescence Resonance Energy Transfer Fluorescent Dyes - chemistry Humans Hydrogen-Ion Concentration Microscopy, Confocal Nanomedicine Organic chemistry pH-responsiveness protein therapeutics Proteins Salicylamides - chemistry Somatostatin - chemistry Somatostatin - metabolism
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