New mechanisms of phenytoin in calcium homeostasis: competitive inhibition of CD38 in hippocampal cells

Purpose Phenytoin is a major anticonvulsant drug that is effective to improve arrhythmia and neuropathic pain. According to early works, phenytoin affected cell membrane depolarization by sodium channel blocking, guanylyl and adenylyl cyclase suppression that cause to intracellular Na + and Ca 2+ do...

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Veröffentlicht in:	Daru 2018-12, Vol.26 (2), p.191-198
Hauptverfasser:	Sadeghi, Leila, Yekta, Reza, Dehghan, Gholamreza
Format:	Artikel
Sprache:	eng
Schlagworte:	Arrhythmia Biomedical and Life Sciences Biomedicine Cell membranes Medicinal Chemistry Oxidative stress Pharmaceutical Sciences/Technology Pharmacology/Toxicology Phenytoin Research Article
Online-Zugang:	Volltext
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