Defective Nrf2-dependent redox signalling contributes to microvascular dysfunction in type 2 diabetes

In type 2 diabetes, antioxidant depletion contributes to increased oxidative stress in the microvasculature. The current study was designed to assess how oxidative stress contributes to functional changes in the microvasculature, and determine the importance, and the effects of pharmacologically tar...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cardiovascular research 2013-10, Vol.100 (1), p.143-150
Hauptverfasser:	Velmurugan, Gopal V, Sundaresan, Nagalingam R, Gupta, Mahesh P, White, Carl
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arterioles - physiopathology Cells, Cultured Diabetes Mellitus, Type 2 - physiopathology Diabetic Angiopathies - etiology Editor's Choice Glutamate-Cysteine Ligase - genetics Glutathione - metabolism Isothiocyanates - pharmacology Male Mice Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - physiology NF-E2-Related Factor 2 - physiology Original Oxidation-Reduction Reactive Oxygen Species - metabolism Signal Transduction - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!