Regulation of an Opioid Receptor Chaperone Protein, RTP4, by Morphine

Signaling by classic analgesics, such as morphine, is governed primarily by the relative abundance of opioid receptors at the cell surface, and this is regulated by receptor delivery to, and retrieval from, the plasma membrane. Although retrieval mechanisms, such as receptor endocytosis, have been e...

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Veröffentlicht in:	Molecular pharmacology 2019-01, Vol.95 (1), p.11-19
Hauptverfasser:	Fujita, Wakako, Yokote, Mini, Gomes, Ivone, Gupta, Achla, Ueda, Hiroshi, Devi, Lakshmi A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics, Opioid - pharmacology Animals Cell Line, Tumor Endocytosis - drug effects Male Mice Mice, Inbred C57BL Molecular Chaperones - metabolism Morphine - pharmacology Narcotic Antagonists - pharmacology Receptors, Opioid, delta - metabolism Receptors, Opioid, mu - metabolism
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