Negative effect of vitamin D on kidney function: a Mendelian randomization study

The kidney plays a central role in the regulation of vitamin D metabolism. It is not clear, however, whether vitamin D influences kidney function. Previous studies have reported conflicting results, which may have been influenced by reverse causation and residual confounding. We conducted a Mendelia...

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Veröffentlicht in:	Nephrology, dialysis, transplantation dialysis, transplantation, 2018-12, Vol.33 (12), p.2139-2145
Hauptverfasser:	Teumer, Alexander, Gambaro, Giovanni, Corre, Tanguy, Bochud, Murielle, Vollenweider, Peter, Guessous, Idris, Kleber, Marcus E, Delgado, Graciela E, Pilz, Stefan, März, Winfried, Barnes, Catriona L K, Joshi, Peter K, Wilson, James F, de Borst, Martin H, Navis, Gerjan, van der Harst, Pim, Heerspink, Hiddo J L, Homuth, Georg, Endlich, Karlhans, Nauck, Matthias, Köttgen, Anna, Pattaro, Cristian, Ferraro, Pietro Manuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Cholestanetriol 26-Monooxygenase - genetics Cytochrome P450 Family 2 - genetics Genome-Wide Association Study Glomerular Filtration Rate Humans Kidney - physiopathology Mendelian Randomization Analysis ORIGINAL ARTICLES Oxidoreductases Acting on CH-CH Group Donors - genetics Polymorphism, Single Nucleotide Vitamin D - blood Vitamins - blood
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