Estimated incidence of perinatally acquired HIV infection in the United States, 1978-2013
BACKGROUND:An incidence of perinatally acquired HIV infection less than 1:100,000 live births is one of the Centers for Disease Control and Prevention (CDC) goals for the United States. Such an estimate has only been possible in recent years, because regular nationwide data were lacking. METHOD:Usin...
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Veröffentlicht in: | Journal of acquired immune deficiency syndromes (1999) 2017-12, Vol.76 (5), p.461-464 |
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container_title | Journal of acquired immune deficiency syndromes (1999) |
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creator | Nesheim, Steven R Wiener, Jeffrey Fitz Harris, Lauren F Lampe, Margaret A Weidle, Paul J |
description | BACKGROUND:An incidence of perinatally acquired HIV infection less than 1:100,000 live births is one of the Centers for Disease Control and Prevention (CDC) goals for the United States. Such an estimate has only been possible in recent years, because regular nationwide data were lacking.
METHOD:Using previously published CDC estimates of the number of infants born with HIV infection in the United States (interpolating for years for which there was no published estimate), and census data on the annual number of live-born infants, estimated incidence was calculated for 1978-2013. Exact 95% confidence intervals were calculated using the Poisson distribution.
RESULTS:Estimated incidence of perinatally acquired HIV infection peaked at 43.1 (95%CI, 41.1-45.1) in 1992, and declined rapidly after the use of zidovudine prophylaxis was recommended in 1994. In 2013, estimated incidence of perinatally acquired HIV infection in the United States was 1.8 (95%CI, 1.4-2.2), a 96% decline since the peak.
CONCLUSION:Estimated incidence of perinatally acquired HIV infection in the United States in 2013 was 1.8/100,000 live births. |
doi_str_mv | 10.1097/QAI.0000000000001552 |
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METHOD:Using previously published CDC estimates of the number of infants born with HIV infection in the United States (interpolating for years for which there was no published estimate), and census data on the annual number of live-born infants, estimated incidence was calculated for 1978-2013. Exact 95% confidence intervals were calculated using the Poisson distribution.
RESULTS:Estimated incidence of perinatally acquired HIV infection peaked at 43.1 (95%CI, 41.1-45.1) in 1992, and declined rapidly after the use of zidovudine prophylaxis was recommended in 1994. In 2013, estimated incidence of perinatally acquired HIV infection in the United States was 1.8 (95%CI, 1.4-2.2), a 96% decline since the peak.
CONCLUSION:Estimated incidence of perinatally acquired HIV infection in the United States in 2013 was 1.8/100,000 live births.</description><identifier>ISSN: 1525-4135</identifier><identifier>EISSN: 1944-7884</identifier><identifier>DOI: 10.1097/QAI.0000000000001552</identifier><identifier>PMID: 28991886</identifier><language>eng</language><publisher>Copyright Wolters Kluwer Health, Inc. All rights reserved</publisher><ispartof>Journal of acquired immune deficiency syndromes (1999), 2017-12, Vol.76 (5), p.461-464</ispartof><rights>Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,777,781,882,27905,27906</link.rule.ids></links><search><creatorcontrib>Nesheim, Steven R</creatorcontrib><creatorcontrib>Wiener, Jeffrey</creatorcontrib><creatorcontrib>Fitz Harris, Lauren F</creatorcontrib><creatorcontrib>Lampe, Margaret A</creatorcontrib><creatorcontrib>Weidle, Paul J</creatorcontrib><title>Estimated incidence of perinatally acquired HIV infection in the United States, 1978-2013</title><title>Journal of acquired immune deficiency syndromes (1999)</title><description>BACKGROUND:An incidence of perinatally acquired HIV infection less than 1:100,000 live births is one of the Centers for Disease Control and Prevention (CDC) goals for the United States. Such an estimate has only been possible in recent years, because regular nationwide data were lacking.
METHOD:Using previously published CDC estimates of the number of infants born with HIV infection in the United States (interpolating for years for which there was no published estimate), and census data on the annual number of live-born infants, estimated incidence was calculated for 1978-2013. Exact 95% confidence intervals were calculated using the Poisson distribution.
RESULTS:Estimated incidence of perinatally acquired HIV infection peaked at 43.1 (95%CI, 41.1-45.1) in 1992, and declined rapidly after the use of zidovudine prophylaxis was recommended in 1994. In 2013, estimated incidence of perinatally acquired HIV infection in the United States was 1.8 (95%CI, 1.4-2.2), a 96% decline since the peak.
CONCLUSION:Estimated incidence of perinatally acquired HIV infection in the United States in 2013 was 1.8/100,000 live births.</description><issn>1525-4135</issn><issn>1944-7884</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNpdkFFLwzAUhYMoTqf_wIf-ADuTNElvXoQxphsMRHSCTyFtb220a2ebOfbvzZgP6n25B-65H5xDyBWjI0Z1evM4no_or2FS8iNyxrQQcQogjoOWXMaCJXJAzvv-PXiUEPqUDDhozQDUGXmd9t6trMcick3uCmxyjNoyWmPnGuttXe8im39uXBccs_lLcJWYe9c2QUW-wmjZuP33kw-Q_jpiOoWYU5ZckJPS1j1e_uwhWd5NnyezePFwP5-MF_GaS81jleZoqWUgFC9UWWRogaW8VFkClJYUqIQMaamFhYwmwK1EaQVAnvGCFTYZktsDd73JVljk2PjO1mbdhVjdzrTWmb-XxlXmrf0yiqsUZBIAcABs29pj13_Umy12pkJb-8owavZ1m1C3-V938g0mWHGu</recordid><startdate>20171215</startdate><enddate>20171215</enddate><creator>Nesheim, Steven R</creator><creator>Wiener, Jeffrey</creator><creator>Fitz Harris, Lauren F</creator><creator>Lampe, Margaret A</creator><creator>Weidle, Paul J</creator><general>Copyright Wolters Kluwer Health, Inc. All rights reserved</general><scope>5PM</scope></search><sort><creationdate>20171215</creationdate><title>Estimated incidence of perinatally acquired HIV infection in the United States, 1978-2013</title><author>Nesheim, Steven R ; Wiener, Jeffrey ; Fitz Harris, Lauren F ; Lampe, Margaret A ; Weidle, Paul J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p2592-67cea0a18462d6fdbea8172f6b3800f08058be0f94a8b0382a5e5a488cb2d1da3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nesheim, Steven R</creatorcontrib><creatorcontrib>Wiener, Jeffrey</creatorcontrib><creatorcontrib>Fitz Harris, Lauren F</creatorcontrib><creatorcontrib>Lampe, Margaret A</creatorcontrib><creatorcontrib>Weidle, Paul J</creatorcontrib><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of acquired immune deficiency syndromes (1999)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nesheim, Steven R</au><au>Wiener, Jeffrey</au><au>Fitz Harris, Lauren F</au><au>Lampe, Margaret A</au><au>Weidle, Paul J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Estimated incidence of perinatally acquired HIV infection in the United States, 1978-2013</atitle><jtitle>Journal of acquired immune deficiency syndromes (1999)</jtitle><date>2017-12-15</date><risdate>2017</risdate><volume>76</volume><issue>5</issue><spage>461</spage><epage>464</epage><pages>461-464</pages><issn>1525-4135</issn><eissn>1944-7884</eissn><abstract>BACKGROUND:An incidence of perinatally acquired HIV infection less than 1:100,000 live births is one of the Centers for Disease Control and Prevention (CDC) goals for the United States. Such an estimate has only been possible in recent years, because regular nationwide data were lacking.
METHOD:Using previously published CDC estimates of the number of infants born with HIV infection in the United States (interpolating for years for which there was no published estimate), and census data on the annual number of live-born infants, estimated incidence was calculated for 1978-2013. Exact 95% confidence intervals were calculated using the Poisson distribution.
RESULTS:Estimated incidence of perinatally acquired HIV infection peaked at 43.1 (95%CI, 41.1-45.1) in 1992, and declined rapidly after the use of zidovudine prophylaxis was recommended in 1994. In 2013, estimated incidence of perinatally acquired HIV infection in the United States was 1.8 (95%CI, 1.4-2.2), a 96% decline since the peak.
CONCLUSION:Estimated incidence of perinatally acquired HIV infection in the United States in 2013 was 1.8/100,000 live births.</abstract><pub>Copyright Wolters Kluwer Health, Inc. All rights reserved</pub><pmid>28991886</pmid><doi>10.1097/QAI.0000000000001552</doi><tpages>4</tpages></addata></record> |
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title | Estimated incidence of perinatally acquired HIV infection in the United States, 1978-2013 |
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