Pharmacokinetics of Sublingually Delivered Fentanyl in Head and Neck Cancer Patients Treated with Curatively Aimed Chemo or Bioradiotherapy

Over 90% of patients treated for head and neck cancer with curatively aimed chemo or bioradiotherapy will develop painful mucositis and xerostomia. Sublingually delivered fentanyl (SDL) is a rapid acting opioid to treat breakthrough pain. It is unclear how SDL is absorbed by the mucosa of these pati...

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Veröffentlicht in:Cancers 2018-11, Vol.10 (11), p.445
Hauptverfasser: Kuip, Evelien J M, Oldenmenger, Wendy H, Oomen-de Hoop, Esther, Verduijn, Gerda M, Thijs-Visser, Martine F, de Bruijn, Peter, van Meerten, Esther, Koolen, Stijn L W, Mathijssen, Ron H J, van der Rijt, Carin C D
Format: Artikel
Sprache:eng
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