A Hyperfluorinated Hydrophilic Molecule for Aqueous 19F MRI Contrast Media

Fluorine-19 (19F) magnetic resonance imaging (MRI) has the potential for a wide range of in vivo applications but is limited by lack of flexibility in exogenous probe formulation. Most 19F MRI probes are composed of perfluorocarbons (PFCs) or perfluoropolyethers (PFPEs) with intrinsic properties whi...

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Veröffentlicht in:	Contrast media and molecular imaging 2018-01, Vol.2018 (2018), p.1-8
Hauptverfasser:	Annapragada, Ananth V., Romero, Jonathan, Ghaghada, Ketan B., Badachhape, Andrew A., Ngwa, Conelius, Devkota, Laxman, Tanifum, Eric A., Pautler, Robia G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Chemical synthesis Chromatography Contrast agents Contrast media Cytotoxicity Design Flexibility Fluorine Genotoxicity Hydrophilicity Magnetic resonance imaging Mutagenesis Mutation NMR Nuclear magnetic resonance Perfluorocarbons Polymers Toxicity
Online-Zugang:	Volltext
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